개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제20권 제4호
- 발행연도
- 2010.1
- 수록면
- 817 - 820 (4page)
이용수
초록· 키워드
오류제보하기
Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by extreme insulin deficiency due to an overall reduction in the mass of functional pancreatic β-cells. Several animal models have been used to study T1DM. Amongst these, the mini-pig seems to be the most ideal model for diabetes research, owing to similarities with humans in anatomy and physiology. The purpose of this study was to analyze differentially expressed pancreatic proteins in a streptozotocin (STZ)-induced mini-pig T1DM model. Pancreas proteins from mini-pigs treated with STZ were separated by two-dimensional gel electrophoresis,and 11 protein spots were found to be altered significantly when compared with control mini-pigs. The data in this study utilizing proteomic analysis provide a valuable resource for the further understanding of the T1DM pathomechanism.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Araki, E / 2003 / Impact of endoplasmic reticulum stress pathway on pancreatic β-cells and diabetes mellitus / Exp. Biol. Med 228 : 1213 ~ 1217
Atkinson, M. A / 2009 / The pancreas in human type I diabetes: Providing new answers to age-old questions / Curr. Opin. Endocrinol. Obes 16 : 279 ~ 285
Canavan, J. P / 1997 / The effect of portal and peripheral insulin delivery on carbohydrate and lipid metabolism in a miniature pig model of human IDDM / Diabetologia 40 : 11
Chatzigeorgiou, A / 2009 / The use of animal model in the study of diabetes mellitus / In Vivo 23 : 245 ~ 258
Giarratana, N / 2007 / Animal models of spontaneous autoimmune disease: Type 1 diabetes in the nonobese diabetic mouse / Methods Mol. Biol 380 : 285 ~ 311
Atkinson, M. A / 2009 / The pancreas in human type I diabetes: Providing new answers to age-old questions / Curr. Opin. Endocrinol. Obes 16 : 279 ~ 285
Canavan, J. P / 1997 / The effect of portal and peripheral insulin delivery on carbohydrate and lipid metabolism in a miniature pig model of human IDDM / Diabetologia 40 : 11
Chatzigeorgiou, A / 2009 / The use of animal model in the study of diabetes mellitus / In Vivo 23 : 245 ~ 258
Giarratana, N / 2007 / Animal models of spontaneous autoimmune disease: Type 1 diabetes in the nonobese diabetic mouse / Methods Mol. Biol 380 : 285 ~ 311
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Genetic Variation and Association Study by Microsatellite Markers Genotyping with Economic Traits in Korean Native Pigs and American Yorkshire Pigs
한국생명과학회 심포지움
2008 .10
-
Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes
Experimental and Molecular Medicine
2014 .01
-
Genetic and Antigenic Characterization of Swine H1N2 Influenza Viruses Isolated from Korean Pigs
Journal of Microbiology and Biotechnology
2007 .01
-
Protein Tyrosine Phosphatase N1 Gene Variants Associated with Type 2 Diabetes Mellitus and Its Related Phenotypes in the Korean Population
Genomics & informatics
2008 .01
-
제 2형 당뇨병 환자의 이환기간에 따른 심혈관계 질환 위험요인 분석
한국영양학회지
2007 .09
-
Recent progress in genetic and epigenetic research on type 2 diabetes
Experimental and Molecular Medicine
2016 .01
-
Stress, Nutrition and Immune Regulation in Pigs
한국미생물학회 학술대회논문집
2016 .04
-
뇌경색 당뇨병 환자와 비뇌경색 당뇨병 환자의 비교연구 : 영양소 섭취, 식사의 질 평가를 중심으로
한국영양학회지
2008 .10
-
Streptozotocin으로 유발한 당뇨 흰쥐의 혈당 및 혈청 지질함량에 미치는 가시오가피 추출물의 영향
동아시아식생활학회지
2005 .10
-
Pathogenesis of Human Norovirus Genogroup II Genotype 4 in Post- Weaning Gnotobiotic Pigs
Journal of Microbiology and Biotechnology
2018 .01
-
Phenotypic and Genotypic Characterization of Salmonella spp. Isolated from Pigs and their Farm Environment in Korea
Journal of Microbiology and Biotechnology
2011 .01
-
The genetic studies of type 2 diabetes mellitus in Japan
한국유전체학회 Conference
2006 .01
-
세포생물학과 Proteomics 응용
미생물학회지
2001 .06
-
Application of Pig Genomic Studies to Agriculture and Life Science
한국유전체학회 Conference
2006 .01
-
A Complete Proteomic Solution
한국생명과학회 학술발표회
2000 .01
-
Development of Optimal Breeding Pigs Using DNA Marker Information
Genomics & informatics
2010 .01
-
천연 생약 복합 추출물이 Streptozotocin 유발 당뇨성 흰쥐의 혈당 및 인슐린, 혈청 과산화지질 농도에 미치는 효과
동아시아식생활학회지
2007 .04
-
보리순 분말이 당뇨쥐의 혈당조절에 미치는 효과
한국지역사회생활과학회지
2016 .02
-
Proteomic Approaches for Industrial Applications
한국미생물학회 학술대회논문집
2006 .05
-
Towards Comprehensive Proteomic Analysis of Cells and Tissues
한국유전체학회 Conference
2002 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0