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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 437 - 444 (8page)
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초록· 키워드
오류제보하기
Vinyl acetate has been widely used for the manufacture of polyvinyl alcohol emulsion, which is primary ingredient of adhesive, paints, textile, paperboard coatings, etc. Since these products are plentiful and frequently used around us, workers and consumers are at health risk. International Agency for Research on Cancer (IARC) classified vinyl acetate as group 2B (possibly carcinogenic to humans). Among the organs targeted, the oral cavity is the most vulnerable organ affected by the carcinogenic effects of vinyl acetate. Since the origin of most of oral cancer is derived from the epithelial cells, it is important to understand the carcinogenic potential of vinyl acetate in human epithelial cells. Thus, the present study has attempted to utilize the immortalized human epithelial cell model to assess the carcinogenic potency of this chemical and to understand the underlying mechanisms.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
/ / Chronic toxicity and oncogenicity inhalation study with vinyl acetate in the rat and mouse : 215 ~ 229
/ / Cytotoxicity and DNAprotein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase mediated : 283 ~ 292
/ / Histochemical localization of aldehyde dehydrogenase in the respiratory tract of the Fischer-344 rat : 560 ~ 567
/ / Induction of chromosome aberrations by styrene and vinyl acetate in cultured human lymphocytes Dependence on erythrocytes (rppa h) : 109 ~ 116
/ / Neoplastic transformation of human epithelial cells in vitro : 1345 ~ 1366
/ / Cytotoxicity and DNAprotein crosslink formation in rat nasal tissues exposed to vinyl acetate are carboxylesterase mediated : 283 ~ 292
/ / Histochemical localization of aldehyde dehydrogenase in the respiratory tract of the Fischer-344 rat : 560 ~ 567
/ / Induction of chromosome aberrations by styrene and vinyl acetate in cultured human lymphocytes Dependence on erythrocytes (rppa h) : 109 ~ 116
/ / Neoplastic transformation of human epithelial cells in vitro : 1345 ~ 1366
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