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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 187 - 192 (6page)
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초록· 키워드
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Objective: To evaluate thyroid function and hormonal profile in women with polycystic ovary syndrome (PCOS).
Methods: A case-control study was conducted at Saad Abualila Center, Khartoum, Sudan. The cases were women with confirmed PCOS based on Rotterdam criteria. The controls were infertile women with no evidence of PCOS. The socio-demographic characteristics and medical history were gathered using a questionnaire. Thyroid hormones (thyroid-stimulating hormone, free tri-iodothyronine, and free thyroxine), anti-thyroid peroxidase, and anti-thyroglobulin antibodies were measured.
Results: While there were no significant differences in the age and haemoglobin levels of the two studied groups (55 women in each arm), body mass index was significantly higher in women with PCOS. There were no significant differences in the levels of thyroid-stimulating hormone, luteinizing hormone, follicle stimulating hormone, luteinizing hormone/ follicle stimulating hormone, anti-thyroid peroxidase, anti-thyroglobulin antibodies, cholesterol, triglycerides and low-density lipoprotein cholesterol between the cases and the controls. The mean±standard deviation of free tri-iodothyronine (3.50±0.2 vs. 3.38±0.3 pg/mL, P=0.040) and median (interquartile) high-density lipoprotein cholesterol (37.0 [34.0 to 42.0] vs. 35.80 [29.0 to 41.0] mg/dL, P=0.015) were significantly higher in PCOS patients compared with the control group. In linear regression, PCOS (0.151 pg/mL, P=0.023) and anti-thyroid peroxidase levels (-0.078 pg/mL, P=0.031) were significantly associated with free tri-iodothyronine.
Conclusion: Free tri-iodothyronine was a significantly higher among PCOS patients compared with the control group.
목차
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참고문헌 (21)
참고문헌 신청
Ahmed M / 2015 / Maternal age and intracytoplasmic sperm injection outcome in infertile couples at Khartoum / Sudan. F1000Res 4 : 1339 ~
Cibula D / 2004 / Is insulin resistance an essential component of PCOS? The influence of confounding factors / Hum Reprod 19 : 757 ~ 759
Elhaj ET / 2015 / Thyroid function/antibodies in Sudanese patients with preeclampsia / Front Endocrinol (Lausanne) 6 : 87 ~
Elussein EA / 2008 / Clinical patterns and major causes of infertility among Sudanese couples / Trop Doct 38 : 243 ~ 244
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults / 2001 / Executive summary of the third report of the National Cholesterol Education
Cibula D / 2004 / Is insulin resistance an essential component of PCOS? The influence of confounding factors / Hum Reprod 19 : 757 ~ 759
Elhaj ET / 2015 / Thyroid function/antibodies in Sudanese patients with preeclampsia / Front Endocrinol (Lausanne) 6 : 87 ~
Elussein EA / 2008 / Clinical patterns and major causes of infertility among Sudanese couples / Trop Doct 38 : 243 ~ 244
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults / 2001 / Executive summary of the third report of the National Cholesterol Education
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