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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 56 - 62 (7page)
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ObjectiveThis study aimed to estimate the association between total and ionized magnesium, and the changes in serum magnesium and calcium levels in patients with preterm labor during magnesium sulfate (MgSO4) administration. MethodsThe study population included 64 women who were candidates for intravenous MgSO4 treatment for preterm labor. Serial blood samples were taken and measured total magnesium (T-Mg), ionized magnesium (I-Mg), total calcium (T-Ca), and ionized calcium (I-Ca) levels every one-week interval (1st, 2nd, 3rd). ResultsThere was no significant difference in T-Mg and I-Mg levels during MgSO4 administration (P>0.05). There was no significant difference in T-Ca and I-Ca levels during MgSO4 administration (P>0.05). Compared before and after administration of MgSO4, T-Mg and I-Mg levels and T-Ca levels were changed allow statistically significant (P<0.05). But, there was no significant difference in the I-Ca serum levels before and after MgSO4 administration (P=0.495). The I-Mg levels for patients with adverse effect were higher than other group but did not reach statistical significance (P>0.05). There was significant correlation between levels of I-Mg and T-Mg (I-Mg=0.395×T-Mg+0.144, P<0.01). ConclusionThere were no significant differences in serum Mg and Ca levels during MgSO4 administration for preterm labor. Compared to the before and after administration of MgSO4, only I-Ca levels were not substantially changed. There are significant correlations between I-Mg and T-Mg levels during administration of MgSO4 and I-Mg level seemed to have more correlation with adverse effect than T-Mg.
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참고문헌 (29)
참고문헌 신청
Elliott JP / 1983 / Magnesium sulfate as a tocolytic agent / Am J Obstet Gynecol 147:277~284
Sibai BM / 1990 / Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia / Am J Obstet Gynecol 162:1141~1145
Rouse DJ / 2008 / A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy / N Engl J Med 359:895~905
American College of Obstetricians / 2010 / Committee Opinion No. 455: magnesium sulfate before anticipated preterm birth for neuroprotection / Obstet Gynecol 115:669~671
1995 / ACOG technical bulletin. Preterm labor. Number 206--June 1995 (replaces no. 133, October 1989) / Int J Gynaecol Obstet 50:303~313
Sibai BM / 1990 / Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia / Am J Obstet Gynecol 162:1141~1145
Rouse DJ / 2008 / A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy / N Engl J Med 359:895~905
American College of Obstetricians / 2010 / Committee Opinion No. 455: magnesium sulfate before anticipated preterm birth for neuroprotection / Obstet Gynecol 115:669~671
1995 / ACOG technical bulletin. Preterm labor. Number 206--June 1995 (replaces no. 133, October 1989) / Int J Gynaecol Obstet 50:303~313
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