메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제30권 제1호
발행연도
2016.1
수록면
17 - 24 (8page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: To describe the changes of fundus autofluorescence (FAF) in patients with age-related macular degenerationbefore and after intravitreal injection of anti-vascular endothelial growth factor according to the typeof choroidal neovascularization (CNV) and to evaluate the correlation of FAF with spectral domain optical coherencetomography (SD-OCT) parameters and vision. Methods: This was a retrospective study. Twenty-one treatment-naïve patients with neovascular age-relatedmacular degeneration were included. Study eyes were divided into two groups according to the type of CNV. Fourteen eyes were type 1 CNV and seven eyes were type 2 CNV. All eyes underwent a complete ophthalmologicexamination, including an assessment of best-corrected visual acuity, SD-OCT, fluorescein angiography,and FAF imaging, before and 3 months after intravitreal anti-vascular endothelial growth factor injection. Gray scales of FAF image for CNV areas, delineated as in fluorescein angiography, were analyzed using theImageJ program, which were adjusted by comparison with normal background areas. Correlation of changesin FAF with changes in SD-OCT parameters, including CNV thickness, photoreceptor inner and outer segmentjunction disruption length, external limiting membrane disruption length, central macular thickness, subretinalfluid, and intraretinal fluid were analyzed. Results: Eyes with both type 1 and type 2 CNV showed reduced FAF before treatment. The mean gray scales (%)of type 1 and type 2 CNV were 52.20% and 42.55%, respectively. The background values were 106.72 and96.86. After treatment, the mean gray scales (%) of type 1 CNV and type 2 CNV were changed to 57.61% (p= 0.005) and 57.93% (p = 0.008), respectively. After treatment, CNV thickness, central macular thickness, andinner and outer segment junction disruption length were decreased while FAF increased. Conclusions: FAF was noted to be reduced in eyes with newly diagnosed wet age-related macular degeneration,but increased after anti-vascular endothelial growth factor therapy regardless of CNV lesion type.

목차

등록된 정보가 없습니다.

참고문헌 (20)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0