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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 143 - 148 (6page)
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초록· 키워드
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Background: Urticarial dermatitis, which is characterised by persistent wheals with eczematous papules and plaques, is frequently misdiagnosed and difficult to treat. Patients commonly experience intolerable pruritus which may greatly affect their quality of life. Objective: The objective of this study is to characterize the clinical patterns of pruritus in patients with urticarial dermatitis and to determine the effectiveness of cyclosporine treatment. Methods: This prospective study included 50 histopathologically confirmed patients with urticarial dermatitis. A face-to-face structured questionnaire was given to all patients, and they were treated with low-dose cyclosporine (1∼3 mg/kg/d) for at least 2 weeks. Results: The majority of patients (80.0%) had moderate to severe pruritus.
Most patients experienced exacerbation of the itch in the evening (74.0%), with the extremities (upper, 86.0%; lower, 94.0%) being the most commonly involved sites. Due to severe pruritus, patients complained about reduced social contact, quality of life and difficulties in falling asleep et al.
Cyclosporine significantly reduced the mean itch score and extent of erythema, and improved interference with daily activities and sleep. Conclusion: Our study highlights the detailed description and characteristics of pruritus in patients with urticarial dermatitis. And we recommend alternative and effective therapeutic option of low-dose cyclosporine.
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등록된 정보가 없습니다.
참고문헌 (11)
참고문헌 신청
Asero R / 2005 / Oral cyclophosphamide in a case of cyclosporin and steroid-resistant chronic urticaria showing autoreactivity on autologous serum skin testing / Clin Exp De
Chaptini C / 2014 / Mycophenolate mofetil as a treatment for urticarial dermatitis / Australas J Dermatol 55 : 275 ~ 278
Haest C / 2011 / Measurement of itching: validation of the Leuven Itch Scale / Burns 37 : 939 ~ 950
Hannon GR / 2014 / Urticarial dermatitis:clinical features, diagnostic evaluation, and etiologic associations in a series of 146 patients at Mayo Clinic (2006∼2012) / J Am A
Irem Eren Erturk / 2012 / Effect of the Pruritus on the Quality of Life: A Preliminary Study / Annals of Dermatology 24 (4) : 406 ~ 412
Chaptini C / 2014 / Mycophenolate mofetil as a treatment for urticarial dermatitis / Australas J Dermatol 55 : 275 ~ 278
Haest C / 2011 / Measurement of itching: validation of the Leuven Itch Scale / Burns 37 : 939 ~ 950
Hannon GR / 2014 / Urticarial dermatitis:clinical features, diagnostic evaluation, and etiologic associations in a series of 146 patients at Mayo Clinic (2006∼2012) / J Am A
Irem Eren Erturk / 2012 / Effect of the Pruritus on the Quality of Life: A Preliminary Study / Annals of Dermatology 24 (4) : 406 ~ 412
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