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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objective: The prevalence rate of osteoarthritis in Koreans aged 50 years or older is 14.3%, and the total amount of medical costsis more than KRW 1 trillion. Recently, the reimbursement guidelines for osteoarthritis treatment have changed. Methods: In thisstudy, we sought to describe prescription patterns of nonsteroidal anti-inflammatory drugs (NSAIDs) and gastro-protective agent(GPA) and analyze the clinical and economic impacts of the new policy using the national health insurance claims data. Theincidence of upper gastrointestinal adverse event by policy change was identified through the odds ratio, and changes in medicineand medical costs related to osteoarthritis through mean and median. Results: There were 204,552 patients before thereimbursement guidelines relaxation and 239,710 after it, a 17.2% rise. The prescription ratio was 3.3% for the patients prescribedwith COX-2 selective NSAIDs alone and 1.3% for those with both COX-2 selective NSAIDs and GPA combination before thereimbursement guidelines relaxation. The reimbursement guidelines relaxation significantly increased their ratios to 6.9% and 2.8%,respectively. Gastrointestinal adverse events significantly reduced by 1.21%p after reimbursement guidelines relaxation. The averagemedicine cost per person increased significantly to KRW 140,291 from KRW 137,323 after the reimbursement guidelines relaxation,while the average medical cost per person slightly decreased from KRW 311,605 to KRW 310,755 after the relaxation, showing nomeaningful difference. Conclusion: The reimbursement guidelines relaxation may influence on decreasing the upper gastrointestinaladverse event, increasing the medicine costs and maintaining the medical costs for osteoarthritis.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
/ / Weighted average price of drugs in 2011 2nd half
/ / Weighted average price of drugs in 2015
Chan FK / 2010 / Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial / Lancet2010 376 (9736) : 1
Chang CH / 2011 / Risk of hospitalization for upper gastrointestinal adverse events associated with nonsteroidal antiinflammatory drugs: a nationwide case-crossover study in
Hochberg MC / 2012 / American college of rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and
/ / Weighted average price of drugs in 2015
Chan FK / 2010 / Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial / Lancet2010 376 (9736) : 1
Chang CH / 2011 / Risk of hospitalization for upper gastrointestinal adverse events associated with nonsteroidal antiinflammatory drugs: a nationwide case-crossover study in
Hochberg MC / 2012 / American college of rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and
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