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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 179 - 189 (11page)
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초록· 키워드
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With the increasing use of nonsteroidal anti-inflammatory drugs (NSAIDs), the incidence of lower gastrointestinal (GI) complications is expected to increase. However, unlike upper GI complications, the burden, pathogenesis, prevention and treatment of NSAID-associated lower GI complications remain unclear. To date, no cost-effective and safe protective agent has been developed that can completely prevent or treat NSAID-related lower GI injuries. Selective COX-2 inhibitors, misoprostol, intestinal microbiota modulation, and some mucoprotective agents have been reported to show protective effects on NSAID-induced lower GI injuries. This review aims to provide an overview of the current evidence on the prevention of NSAID-related lower GI injuries.
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등록된 정보가 없습니다.
참고문헌 (96)
참고문헌 신청
Lanas A / 2005 / A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal anti-inflammatory drug use / Am J Gastroenterol 100:1685~1693
Lanas Á / 2015 / Risk of upper and lower gastrointestinal bleeding in patients taking nonsteroidal anti-inflammatory drugs, antiplatelet agents, or anticoagulants / Clin Gastroenterol Hepatol 13:906~912
Laine L / 2008 / Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac / Gastroenterology 135:1517~1525
Lanas A / 2009 / Time trends and impact of upper and lower gastrointestinal bleeding and perforation in clinical practice / Am J Gastroenterol 104:1633~1641
Lanas A / 2009 / Nonsteroidal anti-inflammatory drugs and lower gastrointestinal complications / Gastroenterol Clin North Am 38:333~352
Lanas Á / 2015 / Risk of upper and lower gastrointestinal bleeding in patients taking nonsteroidal anti-inflammatory drugs, antiplatelet agents, or anticoagulants / Clin Gastroenterol Hepatol 13:906~912
Laine L / 2008 / Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac / Gastroenterology 135:1517~1525
Lanas A / 2009 / Time trends and impact of upper and lower gastrointestinal bleeding and perforation in clinical practice / Am J Gastroenterol 104:1633~1641
Lanas A / 2009 / Nonsteroidal anti-inflammatory drugs and lower gastrointestinal complications / Gastroenterol Clin North Am 38:333~352
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