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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 446 - 455 (10page)
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초록· 키워드
오류제보하기
Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such injuries. This article reviewed the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of small bowel injuries caused by NSAIDs. Small bowel injures by NSAIDs might occur with a similar frequency and extent as those observed in the upper gastrointestinal tract. The pathogenesis of NSAID-induced enteropathy is complex and not clearly understood. The various lesions observed in the small bowel, including petechiae, reddened folds, loss of villi, erosions, and ulcers can be detected by capsule endoscopy. A drug that could prevent or treat NSAID-induced enteropathy has not yet been developed. Therefore, further investigations should be performed to elucidate the pathogenesis of such enteropathy and develop suitable preventive and treatment strategies.
목차
등록된 정보가 없습니다.
참고문헌 (84)
참고문헌 신청
Fries JF / 1991 / Non-steroidal antiinflammatory drug-associated gastropathy: incidence and risk factor models / Am J Med 91:213~222
Smalley WE / 1995 / Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons / Am J Epidemiol 141:539~545
Graham DY / 2005 / Visible small-intestinal mucosal injury in chronic NSAID users / Clin Gastroenterol Hepatol 3:55~59
Maiden L / 2005 / A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy / Gastroenterology 128:1172~1178
Goldstein JL / 2005 / Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo / Clin Gastroenterol Hepatol 3:133~141
Smalley WE / 1995 / Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons / Am J Epidemiol 141:539~545
Graham DY / 2005 / Visible small-intestinal mucosal injury in chronic NSAID users / Clin Gastroenterol Hepatol 3:55~59
Maiden L / 2005 / A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy / Gastroenterology 128:1172~1178
Goldstein JL / 2005 / Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo / Clin Gastroenterol Hepatol 3:133~141
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