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논문 기본 정보

자료유형
학술저널
저자정보
Oh, Pok-Ja (Sahmyook University) Moon, Sun Mi (Korea Cancer Center Hospital)
저널정보
대한종양간호학회 Asian Oncology Nursing Asian Oncology Nursing Vol.19 No.3
발행연도
2019.9
수록면
126 - 134 (9page)

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초록· 키워드

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Purpose: This study was to identify changes in cognitive function and fatigue following chemotherapy in patients with stomach or colorectal cancer. Methods: Of the participants, 67 underwent adjuvant chemotherapy, while 66 healthy participants made up the comparison group. Three assessment tools were used: 1) the Korean Mini-Mental State Examination; 2) Everyday Cognition; 3) Functional Assessment of Chronic Illness Therapy-Fatigue. The questionnaires were administered in three stages, before chemotherapy, towards the end of chemotherapy, and 6 months after the final chemotherapy session. Data were analyzed using descriptive statistics and repeated measures analysis of variance (RM ANOVA). Results: At the post-chemotherapy stage, 38.8% of the patients who underwent adjuvant chemotherapy complained of subjective cognitive impairment and reported greater difficulty in the cognitive domains of attention and concentration, memory, and executive function. RM ANOVA revealed a significant decline in cognitive function after chemotherapy. However, improvement was observed six months after the completion of chemotherapy (F=42.68, p< .001). Cancer-related fatigue also showed similar patterns as observed in the case of cognitive function (F=44.76, p< .001). Conclusion: Chemotherapy was associated with increased cognitive decline and fatigue in cancer patients with cancer. Nursing intervention programs need to be developed to counteract cognitive decline and fatigue in patients undergoing chemotherapy.

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INTRODUCTION
METHODS
RESULTS
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UCI(KEPA) : I410-ECN-0101-2019-512-001252584