지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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This study was carried out to investigate the acute oral toxicity of Chamaecyparis obtusa (C. obtusa) essential oil (CBE) in New Zealand white male and female rabbits. Acute oral treatment with the CBE did not reveal any sign of toxicity or mortality in treated rabbits. The body weight of the rabbits was not affected after a single oral administration of the CBE during the 14-day observation period. In both the hematological and blood biochemical analysis, all parameters of the treated group with 2,000 mg/kg body weight of the CBE were not significantly different than those of the control group. Therefore, the lethal dose 50 of the CBE was estimated to be greater than 2,000 mg/kg body weight in rabbits, which indicated that the CBE is non-toxic. In conclusion, this study suggests that oral administration of the CBE is safe on rabbits.
목차
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참고문헌 (22)
참고문헌 신청
서경아 / 2015 / 편백의 Malassezia furfur 에 대한 항균 및 비듬성 두피 개선 효과 / 아시안뷰티화장품학술지 13(3):285~293
Animal and Plant Quarantine Agency / The guideline for toxicity studies of animal medicinal drugs / QIA Notification 2016-22
Ikei H / 2015 / Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil / J Physiol Anthropol 34:44
Joo SS / 2010 / Effects of essential oil from Chamaecypris obtusa on the development of atopic dermatitis-like skin lesions and the suppression of Th cytokines / J Dermatol Sci 60:122~125
정지영 / 2010 / 편백정유의 항산화와 항균활성에 관한 연구 / 대한미용학회지 6(4):407~417
Animal and Plant Quarantine Agency / The guideline for toxicity studies of animal medicinal drugs / QIA Notification 2016-22
Ikei H / 2015 / Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil / J Physiol Anthropol 34:44
Joo SS / 2010 / Effects of essential oil from Chamaecypris obtusa on the development of atopic dermatitis-like skin lesions and the suppression of Th cytokines / J Dermatol Sci 60:122~125
정지영 / 2010 / 편백정유의 항산화와 항균활성에 관한 연구 / 대한미용학회지 6(4):407~417
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