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Background and Objectives The purposes of this study were to compare the purchase rateand adherence regarding the use of two machines, continuous positive airway pressure (CPAP)and automatic positive airway pressure (APAP), and to determine associated factors affecting thepurchase rate and adherence of PAP in the treatment of severe obstructive sleep apnea (OSA). Subjects and Method From March 2016 to December 2017, 45 patients diagnosed with severeOSA by polysomnography were enrolled in this study. Patients were prescribed CPAP orAPAP by one doctor and allowed to decide whether to purchase the machine after a one-monthlease period, which was identified as the purchase rate. Adherence was identified as using themachine 4 h/night on 70% of nights following the PAP therapy of three months. Results The adherence rate of CPAP (84%) was statistically and significantly higher than APAP(55%) (p=0.033). However, there was no significant difference in the adherence rate betweenCPAP (76%) and APAP (63%). The mean pressure and 95th percentile leak were 8.62 cm H2Oand 12.97 L/min in the CPAP and 10.55 cm H2O and 20.36 L/min in the APAP, respectively. Themean pressure and 95th percentile leak were significantly lower in CPAP than in APAP (p=0.010and p=0.014, respectively). Conclusion Although adherence was not significantly different, the purchase rate was significantlyhigher in the fixed CPAP than in APAP, which may have been influenced by high pressureand leak patients experienced when using the particular PAP machine.

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