지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 7 - 21 (15page)
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초록· 키워드
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Nephrotic syndrome (NS) is a common chronic glomerular disease in children characterized by significant proteinuria with resulting hypoalbuminemia, edema, and hyperlipidemia. Renal biopsy findings of diffuse foot processes effacement on electron microscopy and minimal change disease, focal segmental glomerulosclerosis (FSGS), or diffuse mesangial proliferation on light microscopy. It has been speculated that circulating permeability factors would be implicated in the pathogenesis of NS because they have been reportedly detected in the sera of patients and in experimental models of induced proteinuria. Moreover, a substantial portion of the patients with primary FSGS recurrence shortly after transplantation. This report reviews the current knowledge regarding the role of circulating permeability factors in the pathogenesis of proteinuria in NS and suggests future targeted therapeutic approaches for NS.
목차
등록된 정보가 없습니다.
참고문헌 (137)
참고문헌 신청
Eddy AA / 2003 / Nephrotic syndrome in childhood / Lancet 362:629~639
Sinha A / 2012 / Nephrotic syndrome / Indian J Pediatr 79:1045~1055
Vivarelli M / 2017 / Minimal change disease / Clin J Am Soc Nephrol 12:332~345
Noone DG / 2018 / Idiopathic nephrotic syndrome in children / Lancet 392(10141):61~74
Ha TS / 2013 / Roles of adaptor proteins in podocyte biology / World J Nephrol 2:1~10
Sinha A / 2012 / Nephrotic syndrome / Indian J Pediatr 79:1045~1055
Vivarelli M / 2017 / Minimal change disease / Clin J Am Soc Nephrol 12:332~345
Noone DG / 2018 / Idiopathic nephrotic syndrome in children / Lancet 392(10141):61~74
Ha TS / 2013 / Roles of adaptor proteins in podocyte biology / World J Nephrol 2:1~10
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