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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 53 - 57 (5page)
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초록· 키워드
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Renal cortical necrosis (RCN) is patchy or diffuse ischemic destruction of the renal cortex caused by significantly reduced renal arterial perfusion. It is a rare cause of acute kidney injury (AKI) and is associated with high mortality. Here, we review the case of RCN in a 15-year-old boy who developed AKI. A 15-year-old boy was referred to our hospital from a local hospital due to a sharp decrease in his renal function. He presented with acute flank pain, nausea with vomiting, and oliguria for the past two days. He had taken a single dose of antihistamine for nasal congestion. At our hospital, his peak blood pressure was 148/83 mmHg and he had a high body mass index of 32.9 kg/m2. The laboratory data showed a blood urea nitrogen (BUN) of 28.4 mg/dL, a creatinine of 4.26 mg/dL, and a glomerular filtration rate estimated from the serum cystatin C of 20.2 mL/min/1.73m2. Proteinuria (spot urine protein to creatinine ratio 1.66) with pyuria was observed. Kidney sonography showed parenchymal swelling and increased renal echogenicity. Due to rapidly progressing nephritis, steroid pulse therapy (750 mg/IV) was done on the second day of his admission and the patient showed complete recovery with normal renal function. However, the kidney biopsy findings revealed renal cortical hemorrhagic necrosis. Multifocal, relatively well-circumscribed, hemorrhagic necrotic areas (about 25%) were detected in the tubulointerstitium. Although RCN is an unusual cause of AKI, especially in children, pediatricians should consider the possibility of RCN when evaluating patients with rapidly decreasing renal function.
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참고문헌 (16)
참고문헌 신청
Prakash J / 2015 / Changing picture of renal cortical necrosis in acute kidney injury in developing country / World J Nephrol 4:480~486
Beji S / 2017 / Acute renal cortical necrosis in pregnancy : Clinical course and changing prognosis / Nephrol Ther 13:550~552
Prakash J / 2007 / Decreasing incidence of renal cortical necrosis in patients with acute renal failure in developing countries : a single-centre experience of 22 years from Eastern India / Nephrol Dial Transplant 22:1213~1217
Bloom R / 1973 / Acute renal cortical necrosis. Variable course and changing prognosis / Calif Med 119:1~5
Campbell AC / 1949 / Symmetrical cortical necrosis of the kidneys in infancy and childhood / Arch Dis Child 24:269~285
Beji S / 2017 / Acute renal cortical necrosis in pregnancy : Clinical course and changing prognosis / Nephrol Ther 13:550~552
Prakash J / 2007 / Decreasing incidence of renal cortical necrosis in patients with acute renal failure in developing countries : a single-centre experience of 22 years from Eastern India / Nephrol Dial Transplant 22:1213~1217
Bloom R / 1973 / Acute renal cortical necrosis. Variable course and changing prognosis / Calif Med 119:1~5
Campbell AC / 1949 / Symmetrical cortical necrosis of the kidneys in infancy and childhood / Arch Dis Child 24:269~285
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