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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 69 - 73 (5page)
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초록· 키워드
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Objective: To elucidate the response to steroid therapy and prognosis in patients with acquired idiopathic generalized anhidrosis (AIGA). Method: We reviewed the medical records of patients seen at a tertiary neurology clinic between March 2017 and July 2019. Inclusion criteria required the diagnosis of widely distributed anhidrosis, affecting at least 50% of the entire body, in the absence of any other autonomic or neurologic dysfunction. The diagnosis and distribution of generalized anhidrosis were confirmed using thermoregulatory sweat test. Results: Six male patients were included with a mean age at onset of 32 years (range, 16~43 years). All patients received corticosteroid therapy with five consecutive days of intravenous 1g methylprednisolone and oral prednisolone. Five patients showed good response to steroid therapy. However, decreased sweating reappeared in more than a half of patients (N = 3/5) with a mean interval of 32 days (standard deviation, 7.5) until recurrence. The differentiated findings in patients with recurrence compared to those without were anhidrosis over a wider part of body on quantitative sudomotor axon reflex test and decreased heart rate variability to deep breathing. Conclusion: Corticosteroid therapy was effective in improving AIGA symptoms. However, recurrence rates seem to be high after treatment discontinuation and prognostic factors need to be confirmed.
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등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Nakazato Y / 2004 / Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic transmission / Neurology 63:1476~1480
Munetsugu T / 2017 / Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan / J Dermatol 44:394~400
Ohshima Y / 2016 / Classification of systemic and localized sweating disorders / Perspiration Research 51:7~10
Ohshima Y / 2013 / Treatment of patients with acquired idiopathic generalized anhidrosis / Br J Dermatol 168:430~432
Cao R / 2017 / Prognosis of acquired idiopathic generalized anhidrosis / Journal der Deutschen Dermatologischen Gesellschaft 15:942~945
Munetsugu T / 2017 / Revised guideline for the diagnosis and treatment of acquired idiopathic generalized anhidrosis in Japan / J Dermatol 44:394~400
Ohshima Y / 2016 / Classification of systemic and localized sweating disorders / Perspiration Research 51:7~10
Ohshima Y / 2013 / Treatment of patients with acquired idiopathic generalized anhidrosis / Br J Dermatol 168:430~432
Cao R / 2017 / Prognosis of acquired idiopathic generalized anhidrosis / Journal der Deutschen Dermatologischen Gesellschaft 15:942~945
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