지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Recently, l-deprenyl (selegiline), a relative new antiparkinson`s drug, has been marketed in Korea. As its metabolites, l-methamphetamine and l-amphetamine, are the enantiomers of illicit drugs,d-methamphetamine and d-amphetamine, a method for analysis of enantiomers of methamphetamine and amphetamine in rat urine was investigated. The optical isomers of methamphetamine and amphetamine were analyzed with the chiral derivatizing reagent (S)-(-)-N-(trifluoroacetyl)-prolyl chloride (l-TFP), which was used to form the diastereomers of methamphetamine and amphetamine. And all diastereomers (l-TFP -l-AM, lTFP-d-AM, l-TFP-l-MA & l-TFP-d-MA) were well resolved by capillary gas chromatography. After administration of 10mg/kg l-deprenyl to rat, l-methamphetamine and l-amphetamine were detected without autoracemization to the d form in all urine samples collected during 24hrs, and the ratios of l-amphetamine/l-methamphetamine were 1.1~3.3. l-Amphetamine was detected in only 3 out of 8 urine samples collected during 24~48hrs where as no l-methamphetamine was detected in all cases.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Methamphetamine and Amphetamine Analysis in Hair Samples prepared by Cryogenic Mill
대한약학회 학술대회
2002 .01
-
우리나라에서 남용되는 메스암페타민의 거울상 이성질체분리
약학회지
1997 .01
-
메탐페타민 유사 분별능 시험을 통한 l-디프레닐의 약물남용가능성 평가
약학회지
1998 .01
-
Determination of Methamphetamine and its Metabolite Amphetamine in Biological Fluids from 11 Fatal Gases
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1993 .01
-
Development of the On-site Assay for Methamphetamine
대한약학회 학술대회
2000 .01
-
Augmentation of Regional Cerebral Blood Flow Response by Repeated Administration of Methamphetamine in Rat
Clinical Psychopharmacology and Neuroscience
2003 .01
-
Quantitative Analysis of amphetamines in hair by EI-GC-MS using SIM mode with uncertainty estimation
대한약학회 학술대회
2003 .01
-
GC/MS를 이용한 모발 중 메스암페타민 및 암페타민 분석의 측정불확도 평가
약학회지
2007 .01
-
정신 감정 시 메스암페타민 중독 환자의 정량화 뇌파 비교 분석: 환자-대조군 연구
대한법의학회지
2017 .01
-
Methamphetamine 투여가 흰쥐 뇌 부위별 dopamine, serotonin량에 미치는 영향
약학회지
1990 .01
-
Methamphetamine이 면역장기 및 항체생성 능에 미치는 영향
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1994 .01
-
Simultaneous determination of amphetamine (AM), methamphetamine (MA), methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) by GC/MS in Hair
대한약학회 학술대회
2001 .01
-
Behavioral Sensitization and M1 Muscarinic Acetylcholine Receptor mRNA Expression in Methamphetamine-Administered Mice
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2004 .01
-
Pathological Studies on the Chronic Toxicity of Methamphetamine Administration
한국독성학회지
1993 .12
-
Identification of Impurities in a Sample of Illicitly Synthesized Methamphetamine
대한약학회 학술대회
2003 .01
-
가스크로마토그래피-질량분석기를 이용한 모발에서 암페타민형 각성제 약물의 동시 분석
약학회지
2003 .01
-
Inhibitory Effects of Ginseng Total Saponin on Methamphetamine-induced Striatal Dopamine Increase in Mice
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1997 .01
-
Simultaneous determination of nalbuphine and methamphetamine in drug abuser's urine
대한약학회 학술대회
2003 .01
-
Impurity profiling analysis of methamphetamine synthesized by three different methods
대한약학회 학술대회
2001 .01
-
GC/MS에 의한 한국인의 모발중 Methamphetamine검출
약학회지
1993 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0