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논문 기본 정보

자료유형
학술저널
저자정보
나은희 (한국건강관리협회) 박재영 (한국건강관리협회) 김상인 (한국건강관리협회)
저널정보
한국건강관리협회 한국건강관리협회지 한국건강관리협회지 제3권 제2호
발행연도
2005.1
수록면
181 - 188 (8page)

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Background : Osteopenia has been recognized as one of potential complication of chronic liver diseases. Its correlation with hepatits B virus(HBV) carrier, however, has not been reported. Thus this study was aimed to clarify the relationship between the osteopenia and HBV carrier. Methods : Bone densities in 192 HBV carrier women and 200 healthy women were measured; the lumbar spine and three sites of the proximal femur(neck, Ward's triangle, greater trochanter) by dual-photon absorptiometry. And liver function tests(AST, ALT, Albumin, GGT, ALP) were also performed. Results : Bone densities at the four sites measured, were significantly correlated with one another(r=0.34 to 0.99, P<0.01). Compared with control group, HBV carriers had significant decreases in bone densities of femur(P<0.05), particularly marked at Ward's triangle. A negative correlations between bone densities and serum total alkaline phosphatase were also found(r=-0.44, P<0.01). Conclusions : Osteopenia was more prevalent in HBV carrier, particularly in the groups before-fifties. Serum total alkaline phosphatase was higher in those with reduced bone densities Thus measurement of bone densities seems to be necessary in female HBV carriers.

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