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논문 기본 정보

자료유형
학술저널
저자정보
Lee, Sang-Hyun (College of Pharmacy, Seoul National University, Natural Products Research Institute, Seoul National University) Kim, Kyoung-Soon (College of Pharmacy, Seoul National University) Park, You-Mie (College of Pharmacy, Seoul National University) Shin, Kuk-Hyun (Seokwon Life Science Research Institute) Kim, Bak-Kwang (College of Pharmacy, Seoul National University)
저널정보
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제26권 제1호
발행연도
2003.1
수록면
43 - 46 (4page)

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The anti-oxidant activities of tectochrysin, a major compound of propolis, were investigated. Tectochrysin exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by $CCl_4$-intoxication in rats. Tectochrysin tested exhibited a lipid peroxidation causing a significant decrease in MDA production in TBA-reactant assay. Tectochrysin was strong in the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase, catalase and glutathione peroxidase activities in $CCl_4$-intoxicated rats. These results suggest that tectochrysin possess not only the anti-oxidant, but also the activities in $CCl_4$-intoxicated rats. Especially, tectochrysin was found to cause significant increases in the rat liver cytosolic SOD, catalase, GSH-px activities as well as a significant decrease in the MDA production.

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