지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 145 - 151 (7page)
이용수
초록· 키워드
오류제보하기
Methamphetamine (METH) acts strongly on the nervous system and damages neurons and is known to cause neurodegenerative diseases such as Alzheimer's and Parkinson's. Flavonoids, polyphenolic compounds present in green tea, red wine and several fruits exhibit antioxidant properties that protect neurons from oxidative damage and promote neuronal survival. Especially, epicatechin (EC) is a powerful flavonoid with antibacterial, antiviral, antitumor and antimutagenic effects as well as antioxidant effects. We therefore investigated whether EC could prevent METH-induced neurotoxicity using HT22 hippocampal neuronal cells. EC reduced METH-induced cell death of HT22 cells. In addition, we observed that EC abrogated the activation of ERK, p38 and inhibited the expression of CHOP and DR4. EC also reduced METH-induced ROS accumulation and MMP. These results suggest that EC may protect HT22 hippocampal neurons against METH-induced cell death by reducing ER stress and mitochondrial damage.
목차
등록된 정보가 없습니다.
참고문헌 (1)
참고문헌 신청
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models
Journal of Ginseng Research
2022 .05
-
Korean Red Ginseng inhibits methamphetamine addictive behaviors by regulating dopaminergic and NMDAergic system in rodents
Journal of Ginseng Research
2022 .01
-
Corrigendum to “Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models” [J Ginseng Res 46 (2022) 426-434]
Journal of Ginseng Research
2023 .03
-
Cyanidin-3-glucoside inhibits amyloid β25-35-induced neuronal cell death in cultured rat hippocampal neurons
The Korean Journal of Physiology & Pharmacology
2018 .11
-
Protective effect of the aerial parts of Silybum marianum against amyloid β protein (25-35)-induced neuronal death in cultured neurons
Journal of Biomedical and Translational Research
2016 .12
-
정신 감정 시 메스암페타민 중독 환자의 정량화 뇌파 비교 분석: 환자-대조군 연구
대한법의학회지
2017 .01
-
Postmortem Findings in Two Cases of Chronic Methamphetamine Abuse
대한법의학회지
2021 .08
-
최후통첩게임 및 독재자게임을 통한 메스암페타민 사용자들의 사회적 의사결정에 관한 연구
생물치료정신의학
2024 .10
-
Enhanced Antioxidant and Anticancer Properties of Processed Eucommiae Cortex
Natural Product Sciences
2019 .06
-
Pharmacological Properties of CDBT in Hypoxia-induced Neuronal Cell Injury and Their Underlying Mechanisms
대한한방내과학회지
2019 .01
-
HSPE1 exerts a protective role in oxidative stress-induced hippocampal neuronal cell damage
한국실험동물학회 학술발표대회 논문집
2021 .01
-
Oxidative stress-induced aberrant G9a activation disturbs RE-1-containing neuron-specific genes expression, leading to degeneration in human SH-SY5Y neuroblastoma cells
The Korean Journal of Physiology & Pharmacology
2021 .01
-
메스암페타민(필로폰) 급성 중독으로 유발된 심정지 후 생존한 1례
대한임상독성학회지
2018 .01
-
메스암페타민 검사 양성 환자에 대한 임상적 고찰: 단일기관 연구
대한임상독성학회지
2018 .01
-
메스암페타민 사용 장애에서의 의사결정 지연: 모호함에서 위험으로의 전환 지연
생물치료정신의학
2024 .10
-
The deletion of Peroxiredoxin 5 aggravates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus
한국실험동물학회 학술발표대회 논문집
2020 .07
-
A case of methamphetamine intoxication in an adolescent
대한소아응급의학회지
2023 .01
-
Different Ways to Die: Cell Death Pathways and Their Association With Spinal Cord Injury
Neurospine
2023 .06
-
A Fatal Intracerebral Hemorrhage due to Chronic Methamphetamine Use
대한법의학회지
2018 .01
-
Korean Red Ginseng alleviates neuroinflammation and promotes cell survival in the intermittent heat stress-induced rat brain by suppressing oxidative stress via estrogen receptor beta and brain-derived neurotrophic factor upregulation
Journal of Ginseng Research
2020 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0