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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 241 - 253 (13page)
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초록· 키워드
오류제보하기
Flavonoids are major plant constituents with numerous biological/pharmacological actions both in vitro and in vivo. Of these actions, their anti-inflammatory action is prominent. They can regulate transcription of many proinflammatory genes such as cyclooxygenase-2/inducible nitric oxide synthase and many cytokines/chemokines. Recent studies have demonstrated that certain flavonoid derivatives can affect pathways of inflammasome activation and autophagy. Certain flavonoids can also accelerate the resolution phase of inflammation, leading to avoiding chronic inflammatory stimuli. All these pharmacological actions with newly emerging activities render flavonoids to be potential therapeutics for chronic inflammatory disorders including arthritic inflammation, meta-inflammation, and inflammaging. Recent findings of flavonoids are summarized and future perspectives are presented in this review.
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등록된 정보가 없습니다.
참고문헌 (174)
참고문헌 신청
Adlercreutz H / 1993 / Plasma concentrations of phyto-oestrogens in Japanese men / Lancet 342:1209~1210
Alexander E / 2013 / IκBζ is a regulator of the senescence-associated secretory phenotype in DNA damage-and oncogene-induced senescence / J. Cell Sci 126:3738~3745
Alimbetov D / 2016 / Suppression of the senescence-associated secretory phenotype(SASP)in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2 / Biogerontology 17:305~315
Amano SU / 2014 / Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation / Cell Metab 19:162~171
Anders HJ / 2011 / Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis / Kidney Int 80:915~925
Alexander E / 2013 / IκBζ is a regulator of the senescence-associated secretory phenotype in DNA damage-and oncogene-induced senescence / J. Cell Sci 126:3738~3745
Alimbetov D / 2016 / Suppression of the senescence-associated secretory phenotype(SASP)in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2 / Biogerontology 17:305~315
Amano SU / 2014 / Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation / Cell Metab 19:162~171
Anders HJ / 2011 / Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis / Kidney Int 80:915~925
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