지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 419 - 425 (7page)
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초록· 키워드
오류제보하기
Objective : Acute vertebrobasilar artery occlusion (AVBAO) is a devastating disease with a high mortality rate. One of the most important factors affecting favorable clinical outcome is early recanalization. Mechanical thrombectomy is an emerging treatment strategy for achieving a high recanalization rates. However, thrombectomy alone can be insufficient to complete recanalization, especially for acute stroke involving large artery atheromatous disease. The purpose of this study is to investigate the safety and efficacy of mechanical thrombectomy in AVBAO. Methods : Fourteen consecutive patients with AVBAO were treated with mechanical thrombectomy. Additional multimodal treatments were intra-arterial (IA) thrombolysis, balloon angioplasty, or permanent stent placement. Recanalization by thrombectomy alone and multimodal treatments were assessed by the Thrombolysis in Cerebral Infarction (TICI) score. Clinical outcome was determined using the National Institutes of Health Stroke Scale (NIHSS) at 7 days and the modified Rankin Scale (mRS) at 3 months. Results : Thrombectomy alone and multimodal treatments were performed in 10 patients (71.4%) and 4 patients (28.6%), respectively. Successful recanalization (TICI 2b-3) was achieved in 11 (78.6%). Among these 11 patients, 3 (27.3%) underwent multimodal treatment due to underlying atherosclerotic stenosis. Ten (71.4%) of the 14 showed NIHSS score improvement of >10. Overall mortality was 3 (21.4%) of 14. Conclusion : We suggest that mechanical thrombectomy is safe and effective for improving recanalization rates in AVBAO, with low complication rates. Also, in carefully selected patients after the failure of recanalization by thrombectomy alone, additional multimodal treatment such as IA thrombolysis, balloons, or stents can be needed to achieve successful recanalization.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Adams HP Jr. / 1993 / Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment / Stroke 24:35~41
Andersson T. / 2013 / Mechanical thrombectomy as the primary treatment for acute basilar artery occlusion : experience from 5 years of practice / J Neurointerv Surg 5:221~225
Archer CR. / 1977 / Basilar artery occlusion : clinical and radiological correlation / Stroke 8:383~390
Brekenfeld C. / 2011 / Impact of retrievable stents on acute ischemic stroke treatment / AJNR Am J Neuroradiol 32:1269~1273
Caplan LR. / 2004 / New England Medical Center Posterior Circulation registry / Ann Neurol 56:389~398
Andersson T. / 2013 / Mechanical thrombectomy as the primary treatment for acute basilar artery occlusion : experience from 5 years of practice / J Neurointerv Surg 5:221~225
Archer CR. / 1977 / Basilar artery occlusion : clinical and radiological correlation / Stroke 8:383~390
Brekenfeld C. / 2011 / Impact of retrievable stents on acute ischemic stroke treatment / AJNR Am J Neuroradiol 32:1269~1273
Caplan LR. / 2004 / New England Medical Center Posterior Circulation registry / Ann Neurol 56:389~398
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