지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 363 - 367 (5page)
이용수
초록· 키워드
오류제보하기
Objective : The purpose of this study was to evaluate the clinical utility and validity of using a pupillometer to assess patients with acute brain lesions. Methods : Pupillary examinations using an automated pupillometer ($NeurOptics^{(R)}NPi^{TM}$-100 Pupillometer) were performed every 4 hours and were simultaneously assessed using the Glasgow Coma Scale (GCS) and for intracranial pressure (ICP), from admission to discharge or expire in neuro-intensive care unit (NICU). Manual pupillary examinations were also recorded for comparison. By comparing these data, we evaluated the validity of using automated pupillometers to predict clinical outcomes. Results : The mean values of the Neurologic Pupillary index (NPi) were different in the groups examined manually. The GCS correlated well with NPi values, especially in severe brain injury patients (GCS below 9). However, the NPi values were weakly correlated with intracranial pressure (ICP) when the ICP was lower than 30 cm $H_2O$. The NPi value was not affected by age or intensity of illumination. In patients with a "poor" prognosis who had a Glasgow Outcome Scale (GOS) of 1 or 2, the mean initial NPi score was $0.88{\pm}1.68$, whereas the value was $3.89{\pm}0.97$ in patients with a "favorable" prognosis who had a GOS greater than 2 (p<0.001). For predicting clinical outcomes, the initial NPi value of 3.4 had the highest sensitivity and specificity. Conclusion : An automated pupillometer can serve as a simple and useful tool for the accurate measurement of pupillary reactivity in patients with acute brain lesions.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Behrends M. / 2012 / Infrared pupillometry to detect the light reflex during cardiopulmonary resuscitation : a case series / Resuscitation 83:1223~1228
Chang DS. / 2013 / Development and validation of an associative model for the detection of glaucoma using pupillography / Am J Ophthalmol 156:1285.e2~1296.e2
Chen JW. / 2011 / Pupillary reactivity as an early indicator of increased intracranial pressure : the introduction of the Neurological Pupil index / Surg Neurol Int 2:82
Chen JW. / 2014 / Infrared pupillometry, the Neurological Pupil index and unilateral pupillary dilation after traumatic brain injury : implications for treatment paradigms / Springerplus 3:548
Cohen LM. / 2015 / A novel computerized portable pupillometer detects and quantifies relative afferent pupillary defects / Curr Eye Res 40:1120~1127
Chang DS. / 2013 / Development and validation of an associative model for the detection of glaucoma using pupillography / Am J Ophthalmol 156:1285.e2~1296.e2
Chen JW. / 2011 / Pupillary reactivity as an early indicator of increased intracranial pressure : the introduction of the Neurological Pupil index / Surg Neurol Int 2:82
Chen JW. / 2014 / Infrared pupillometry, the Neurological Pupil index and unilateral pupillary dilation after traumatic brain injury : implications for treatment paradigms / Springerplus 3:548
Cohen LM. / 2015 / A novel computerized portable pupillometer detects and quantifies relative afferent pupillary defects / Curr Eye Res 40:1120~1127
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