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자료유형
학술저널
저자정보
Bose, Anindya (Institute of Pharmacy and Technology) Mondal, Sumanta (Institute of Pharmacy and Technology) Gupta, Jayanta Kumar (Department of Pharmaceutical Technology, Jadavpur University) Ghosh, Tirtha (Institute of Pharmacy and Technology) Debbhuti, Debabrata (Gupta College of Technological Sciences) Si, Sudam (School of Pharmaceutical Sciences, Institute for Technical Education and Research)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제8권 제2호
발행연도
2008.1
수록면
135 - 145 (11page)

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The study was aimed at evaluating the antioxidant and free radical scavenging activities of ethanolic extract and its fractions of Cleome rutidosperma. The antioxidant activity, reducing power, total phenolic content, total flavonoid content, superoxide anion scavenging activity, nitric oxide anion scavenging activity, in vitro antilipid peroxidation activity and in vitro non-enzymatic hemoglobin glycosylation were studied. The results obtained in the study indicate that Cleome rutidosperma is a potential source of natural antioxidant. All the parameters were found to be concentration dependent and increased with increasing amounts of sample. Flavonoids, phenolic compound like tannins, terpenoids may be responsible for the antioxidant activity of the plant. Variation of solubility parameters in various models may be attributed to non-linearity of activity of ethanol extract fractions models. Further investigation on the isolation and identification of antioxidant component(s) in the plant may lead to chemical entities with potential for clinical use.

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