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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.5
- 수록면
- 137 - 137 (1page)
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초록· 키워드
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Sweetness is the taste of sugar and is known to be preferred by most animals. However, excessive sugar intake can cause number of adult diseases such as diabetes, hypertension, and obesity which are a big issue in modern society. Therefore, there is an increasing need for sugar substitutes to replace sugar. So, we want to study sweet tasting proteins that taste sweet even though they are proteins, not sugar. For this, a study on the mechanism for sweetness perception is essential.
To understand the mechanism of sweet taste perception, structural and kinetic analysis of sweet-tasting proteins and sweet receptor interactions is important However, to date, the accumulation of sweet taste receptor subunits still presents serious obstacles to both structural and kinetic analysis, so there is also no way to investigate the kinetics of the interaction.
Here we can obtain a heterodimeric human sweet taste receptor in the mammalian expression system using HEK293A and employing SiMPull assay to evaluat^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10558010');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
To understand the mechanism of sweet taste perception, structural and kinetic analysis of sweet-tasting proteins and sweet receptor interactions is important However, to date, the accumulation of sweet taste receptor subunits still presents serious obstacles to both structural and kinetic analysis, so there is also no way to investigate the kinetics of the interaction.
Here we can obtain a heterodimeric human sweet taste receptor in the mammalian expression system using HEK293A and employing SiMPull assay to evaluat^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10558010');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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