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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 99 - 108 (10page)
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초록· 키워드
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Background Lung transplantation (LT) is an accepted therapeutic modality for end-stage lung disease patients. Intensive care unit (ICU) readmission is a risk factor for mortality after LT, for which consistent risk factors have not been elucidated. Thus, we investigated the risk factors for ICU readmission during index hospitalization after LT, particularly regarding the posttransplant condition of LT patients. Methods In this retrospective study, we investigated all adult patients undergoing LT between October 2012 and August 2017 at our institution. We collected perioperative data from electronic medical records such as demographics, comorbidities, laboratory findings, ICU readmission, and in-hospital mortality. Results We analyzed data for 130 patients. Thirty-two patients (24.6%) were readmitted to the ICU 47 times during index hospitalization. At the initial ICU discharge, the Sequential Organ Failure Assessment (SOFA) score (odds ratio [OR], 1.464; 95% confidence interval [CI], 1.083?1.978; P=0.013) and pH (OR, 0.884; 95% CI, 0.813?0.962; P=0.004; when the pH value increases by 0.01) were related to ICU readmission using multivariable regression analysis and were still significant after adjusting for confounding factors. Thirteen patients (10%) died during the hospitalization period, and the number of ICU readmissions was a significant risk factor for in-hospital mortality. The most common causes of ICU readmission and in-hospital mortality were infection-related. Conclusions The SOFA score and pH were associated with increased risk of ICU readmission. Early postoperative management of these factors and thorough posttransplantation infection control can reduce ICU readmission and improve the prognosis of LT patients.
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참고문헌 (21)
참고문헌 신청
Rutherford RM / 2005 / Functional status and quality of life in patients surviving 10 years after lung transplantation / Am J Transplant 5:1099~1104
Wolfe RA / 2010 / Trends in organ donation and transplantation in the United States, 1999-2008 / Am J Transplant 10(4 Pt 2):961~972
Rosenberg AL / 2001 / Who bounces back? Physiologic and other predictors of intensive care unit readmission / Crit Care Med 29:511~518
Rosenberg AL / 2000 / Patients readmitted to ICUs : a systematic review of risk factors and outcomes / Chest 118:492~502
Snow N / 1985 / Readmission of patients to the surgical intensive care unit : patient profiles and possibilities for prevention / Crit Care Med 13:961~964
Wolfe RA / 2010 / Trends in organ donation and transplantation in the United States, 1999-2008 / Am J Transplant 10(4 Pt 2):961~972
Rosenberg AL / 2001 / Who bounces back? Physiologic and other predictors of intensive care unit readmission / Crit Care Med 29:511~518
Rosenberg AL / 2000 / Patients readmitted to ICUs : a systematic review of risk factors and outcomes / Chest 118:492~502
Snow N / 1985 / Readmission of patients to the surgical intensive care unit : patient profiles and possibilities for prevention / Crit Care Med 13:961~964
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