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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 155 - 163 (9page)
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초록· 키워드
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Coronavirus disease 2019 (COVID-19) can reportedly manifest as an acute stroke, with most cases presenting as large vessel ischemic stroke in patients with or without comorbidities. The exact pathomechanism of stroke in COVID-19 remains ambiguous. The findings of previous studies indicate that the most likely underlying mechanisms are cerebrovascular pathological conditions following viral infection, inflammation-induced endothelial dysfunction, and hypercoagulability. Acute endothelial damage due to inflammation triggers a coagulation cascade, thrombosis propagation, and destabilization of atherosclerosis plaques, leading to largevessel occlusion and plaque ulceration with concomitant thromboemboli, and manifests as ischemic stroke. Another possible mechanism is the downregulation of angiotensin-converting enzyme 2 as the target action of severe acute respiratory syndrome-coronavirus-2 (SARSCoV- 2). Acute stroke management protocols need to be modified during the COVID-19 pandemic in order to adequately manage stroke patients with COVID-19.
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등록된 정보가 없습니다.
참고문헌 (68)
참고문헌 신청
World Health Organization / WHO Timeline - COVID-19
Li X / 2020 / Molecular immune pathogenesis and diagnosis of COVID-19 / J Pharm Anala 10:102~108
Huang C / 2020 / Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China / Lancet 395:497~506
Wang D / 2020 / Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-infected pneumonia in Wuhan, China / JAMA 323:1061~1069
Zhou F / 2020 / Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China : a retrospective cohort study / Lancet 395:1054~1062
Li X / 2020 / Molecular immune pathogenesis and diagnosis of COVID-19 / J Pharm Anala 10:102~108
Huang C / 2020 / Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China / Lancet 395:497~506
Wang D / 2020 / Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-infected pneumonia in Wuhan, China / JAMA 323:1061~1069
Zhou F / 2020 / Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China : a retrospective cohort study / Lancet 395:1054~1062
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