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논문 기본 정보

자료유형
학술저널
저자정보
Lim Ji-Eun (Department of Medicine Korea University College of Medicine) Kim Seoyeon (Department of Medicine Korea University College of Medicine) Seo Surin (Department of Medicine Korea University College of Medicine) Kang Wooyoung (Department of Biomedical Sciences Korea University College of Medicine) Kim Aram (Department of Biomedical Sciences Korea University College of Medicine) Kang Youbin (Department of Biomedical Sciences Korea University College of Medicine) Choi Kwan Woo (Department of Psychiatry Korea University Anam Hospital Korea University College of Medicine) Tae Woo-Suk (Brain Convergence Research Center Korea University College of Medicine) Ham Byung-Joo (Department of Psychiatry Korea University Anam Hospital Korea University College of Medicine) Han Kyu-Man (Department of Psychiatry Korea University Anam Hospital Korea University College of Medicine)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제18권 제6호
발행연도
2021.1
수록면
570 - 579 (10page)

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Objective Studies have been conducted to identify brain structural alterations related to high impulsivity in psychiatric populations. However, research on healthy subjects is relatively less extensive. Therefore, we aimed to investigate the correlation between the cortical thickness of whole brain regions and the impulsivity level in a healthy population.Methods We included 100 healthy participants aged 19?65 years. Their T1-weighted magnetic resonance images and the 23-item Barratt Impulsiveness Scale (BIS) score were obtained. The patients were divided into high and low impulsivity groups according to the 75th percentile score of the BIS in the sample. The thickness of each cortical region was calculated using the FreeSurfer, and the difference in cortical thickness of the whole brain between the high and low impulsivity groups was analyzed using one-way analysis of covariance including age, sex, education level, and total intracranial cavity volume as covariates.Results The high impulsivity group showed significant cortical thinning in the left pars opercularis. The cortical thickness of the left pars opercularis significantly correlated negatively with the total, attention, and motor scores of the BIS scale.Conclusion Our findings suggest that prefrontal cortex thinning may play an important role in the development of high impulsivity in healthy adults.

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