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자료유형
학술저널
저자정보
Hyung Yoon Kim (Chonnam National University Hospital) Sung-A Chang (Sungkyunkwan University School of Medicine) Kye Hun Kim (Chonnam National University) Jae-Young Kim (Sungkyunkwan University) Woo-Keun Seo (Sungkyunkwan University) Hyung Seop Kim (Keimyung University College of Medicine) Jeong-Sook Seo (Inje University) Sung Hee Shin (Inha University) Sang Jae Rhee (Wonkwang University Hospital) Sun Hwa Lee (Jeonbuk National University) Jung Sun Cho (The Catholic University of Korea)
저널정보
한국심초음파학회 Journal of Cardiovascular Imaging Journal of Cardiovascular Imaging 제29권 제3호
발행연도
2021.1
수록면
265 - 278 (14page)

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BACKGROUND: The annual incidence of venous thromboembolism (VTE) is increasing, and the treatment pattern of oral anticoagulants (OACs) has changed with introduction of new oral anticoagulants (NOACs). The aims of this study were to assess the annual incidence of VTE in a Korean population and the change of treatment pattern with availability of NOACs using a population-based database. METHODS: Using the Korean National Health Insurance Services database, we identified patients diagnosed with VTE between 2009 and 2016. The annual prevalence of VTE and clinical characteristics and treatment pattern were investigated. The annual incidence of VTE was calculated using direct and indirect methods using the estimated Korean population in 2009 as the reference. RESULTS: The annual incidence of VTE in Korean has increased yearly from 23.9 per 100,000 in 2009 to 42.2 in 2016. The overall rate of OAC prescription for VTE treatment increased from 55.9% to 68% in the same time period. The rate of initiation of NOAC treatment greatly increased, particularly from 2013 onwards, with a 20-fold increase from 2009 to 2016 (2.1% vs. 54.3%). CONCLUSIONS: The annual incidence of VTE in Korea increased by almost two-fold from 2009 to 2016. The rate of initiation of NOAC treatment has increased substantially since 2013, and these agents have surpassed VKAs as the anticoagulant of choice for VTE. This temporal pattern of OAC prescription is consistent with the current clinical guidelines, which indicate NOACs over the warfarin in patients with VTE.

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