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논문 기본 정보

자료유형
학술저널
저자정보
Huanbutta Kampanart (Burapha University Thailand) Sittikijyothin Wancheng (Burapha University Thailand) Sangnim Tanikan (Burapha University Thailand)
저널정보
한국약제학회 Journal of Pharmaceutical Investigation Journal of Pharmaceutical Investigation 제50권 제6호
발행연도
2020.1
수록면
625 - 634 (10page)

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Purpose Propolis extract is an extraction of a resinous mixture of honey bees produced by mixing saliva and beeswax with exudate gathered from tree. The prominent pharmacological activities of propolis extract are antioxidant, antimicrobial, fungicidal, antiviral, antiulcer, immune-stimulating, and cytostatic, which are very suitable for topical formulation. Methods From its various pharmacological activities, propolis extract was formulated in film forming system using modified tamarind seed gum as a solution/gel/film forming agent. To obtain the optimum seed gum concentration of the film forming system (solution to film), various tamarind concentrations and solvent ratios were evaluated. Results The formulation of 7.5% of modified tamarind seed gum with 1% PEG400 dissolved in 55%:45% of water:ethanol provided fast drying time (4.36 min) and proper rheological property for spaying application. The propolis extract loaded formulation could inhibit Staphylococcus aureus and Staphylococcus epidermidis. Moreover, the product satisfaction evaluation was excellent (3.8 from 5). Conclusion The results indicate the possibility of introducing modified tamarind seed gum and propolis extract as a component in the development of film forming systems and increasing the effectiveness of antibacterial on the skin.

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