메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Dongju Kim (Department of Surgery Daejeon St. Mary’s Hospital College of Medicine The Catholic University of Ko) Soo Jung Lee (Department of Surgery Yeungnam University Medical Center Deagu) Byung Kyun Ko (Department of Surgery Ulsan University Hospital Ulsan) Han-Byoel Lee (Department of Surgery Seoul National University College of Medicine Seoul) Jung Han Yoon (Department of Surgery Chonnam National University Hwasun Hospital Hwasun) Seok Won Lee (Department of Surgery Pusan National University Hospital Busan) Ye Won Jeon (Department of Surgery The Catholic University of Korea St. Vincent’s Hospital Suwon Korea) Bong Kyun Kim (Department of Surgery Daejeon St. Mary’s Hospital College of Medicine The Catholic University of Ko) Jina Lee (Department of Surgery Daejeon St. Mary’s Hospital College of Medicine The Catholic University of Ko) Woo Young Sun (Department of Surgery Daejeon St. Mary’s Hospital College of Medicine The Catholic University of Ko)
저널정보
한국유방암학회 Journal of Breast Disease Journal of Breast Disease 제8권 제2호
발행연도
2020.1
수록면
92 - 99 (8page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: Palpability is known to be a poor prognostic factor for breast cancer. The present study analyzed the clinicopathological characteristics and outcomes of palpable and nonpalpable breast cancers using big data. Methods: Between January 2005 and May 2019, a total of 15,141 patients were enrolled. All patients were diagnosed with invasive ductal carcinomas. Patients with unclear medical records, multiple tumors, bilateral breast cancers, inflammatory breast cancers, inoperable breast cancers and distant metastasis were excluded. Patients were divided into the palpable and nonpalpable breast cancer groups based on physicians’ clinical examinations. The clinicopathological characteristics and disease-specific survivals (DSS) were analyzed. Results: Patients with palpable breast cancers were younger, had larger tumors, and higher tumor-node-metastasis stage (p<0.001) than patients with nonpalpable breast cancers. Palpable breast cancer cases had higher rates of lympho-vascular invasion, higher histologic and nuclear grades than nonpalpable breast cancer cases (p<0.001). The positive proportion of hormone receptor was higher in the nonpalpable breast cancer group than in the palpable breast cancer group, but that of human epidermal growth factor receptor 2 was higher in the palpable breast cancer group than in the nonpalpable breast cancer group (p<0.001). The Ki-67 index was higher in the palpable breast cancer group than in the nonpalpable breast cancer group (p<0.001). Total mastectomy and axillary dissection were performed more frequently in the palpable breast cancer group than in the nonpalpable breast cancer group (p<0.001). Adjuvant chemotherapy was administered more frequently in the palpable breast cancer group than in the nonpalpable breast cancer group. However, radiotherapy and hormonal therapy were performed more frequently in nonpalpable breast cancer group than in the nonpalpable breast cancer group (p<0.001). According to a multivariate analysis, younger age, lower body mass index, larger tumor size, tumor location, higher stage, higher histologic grade and higher Ki-67 index were associated with palpability (p<0.001). DSS was significantly lower in the palpable breast cancer group than in the nonpalpable breast cancer group (p<0.001). Conclusion: Palpable breast cancers tend to be triple negative breast cancers and have higher histologic grade and, Ki-67 index and worse prognosis than nonpalpable breast cancers. Therefore, based on the results of the present study, treating palpable breast cancers requires careful attention.
#Breast neoplasms #Carcinoma #Palpation

목차

등록된 정보가 없습니다.

참고문헌 (18)

참고문헌 신청
Independent UK panel on breast cancer screening / 2012 / The benefits and harms of breast cancer screening: an independent review / Lancet 380:1778~1786 google schola Myers ER / 2015 / Benefits and harms of breast cancer screening : a systematic review / JAMA 314:1615~1634 google schola Jorgensen KJ / 2009 / Overdiagnosis in publicly organised mammography screening programmes : systematic review of incidence trends / BMJ 339:b2587 google schola Kalager M / 2012 / Overdiagnosis of invasive breast cancer due to mammography screening : results from the Norwegian screening program / Ann Intern Med 156:491~499 google schola Bjurstam N / 2003 / The Gothenburg breast screening trial / Cancer 97:2387~2396 google schola

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0