지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제22권 제1호
- 발행연도
- 2021.1
- 수록면
- 63 - 69 (7page)
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초록· 키워드
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A one-year-old, intact male Maltese was referred with dehydration, anorexia, and marked hyperglycemia. The dog had been managed due to meningoencephalitis of unknown etiology (MUE) for three months. The dog had been treated with long-term prednisolone administration. Diabetic ketoacidosis (DKA) was identified based on the blood chemistry and venous gas analyses, and intensive treatments including insulin administration were initiated. On further examinations, there was no any other disease that contributed to the occurrence of DKA. Insulin resistance resulted from the administration of prednisolone was highly suspected, but the agent could not be tapered due to managing MUE. Following resolution of DKA, the dog was discharged with life-long insulin and prednisolone therapy. Over the next two years, the dog continued to be routinely re-evaluated and was managed with permanent insulin therapy (0.8?1.4 units/kg SC 12 hourly) and medications including prednisolone (0.4?1.1 mg/kg PO 12 hourly). Because MUE severely progressed, the dog was euthanized by owner’s request. Histopathologic examination of pancreas obtained by post-mortem revealed that both endo- and exocrine pancreas was within normal limit. The case described herein showed the risk of ketoacidosis as well as hyperglycemia after long-term prednisolone administration in a dog without pancreatic islet pathology.
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Radhakutty A / 2018 / Management of endocrine disease : critical review of the evidence underlying management of glucocorticoid-induced hyperglycaemia / Eur J Endocrinol 179:R207~R218
Campbell K / 1984 / Transient diabetes mellitus associ-ated with prednisone therapy in a dog / J Am Vet Med Assoc 198:1645~1648
Jeffers JG / 1991 / Diabetes mellitus induced in a dog after administration of corticosteroids and methylprednisolone pulse therapy / J Am Vet Med Assoc 199:77~80
Nelson RW / 2014 / Animal models of disease : classifi-cation and etiology of diabetes in dogs and cats / J Endo-crinol 222:T1~T9
Parsons SE / 2002 / Endogenous serum insulin concentration in dogs with diabetic ketoacidosis / J Vet Emerg Crit Care 12:147~152
Campbell K / 1984 / Transient diabetes mellitus associ-ated with prednisone therapy in a dog / J Am Vet Med Assoc 198:1645~1648
Jeffers JG / 1991 / Diabetes mellitus induced in a dog after administration of corticosteroids and methylprednisolone pulse therapy / J Am Vet Med Assoc 199:77~80
Nelson RW / 2014 / Animal models of disease : classifi-cation and etiology of diabetes in dogs and cats / J Endo-crinol 222:T1~T9
Parsons SE / 2002 / Endogenous serum insulin concentration in dogs with diabetic ketoacidosis / J Vet Emerg Crit Care 12:147~152
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