지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제21권 제3호
- 발행연도
- 2020.1
- 수록면
- 137 - 142 (6page)
이용수
초록· 키워드
오류제보하기
A 4-year-old, female, Maltese dog with bilateral hind limb ataxia was brought to Gyeongsang National University Animal Medical Center (GAMC). Based on the previous medical and imaging records, the patient was presumptively diagnosed with a primary brain tumor of the right temporo-occipital lobe on magnetic resonance imaging (MRI) in a local animal hospital. Hydroxyurea and prednisolone therapy was initiated, and the neurological signs transiently improved. Approximately 5 months after the treatment, ataxia recurred and the patient was referred to GAMC. Upon admission, MRI at the same anatomic level as in the previous MRI was performed. Results showed inflammatory brain lesions, not brain neoplastic changes. Considering this finding, the dog was tentatively diagnosed with meningoencephalitis of unknown etiology (MUE). We added oral imatinib mesylate (10 mg/kg every 24 h), and the dosage of prednisolone was increased to 1 mg/kg twice daily. Hydroxyurea was discontinued. A rapid improvement in neurological signs was observed after the initiation of imatinib mesylate treatment. Approximately 2 months after the treatment, the size of the inflammatory lesion remarkably decreased on repeat MRI. The patient had been doing well, and there were no overt neurological signs 259 days after the initiation of imatinib mesylate therapy. We describe a case of MUE in a dog that was successfully managed with imatinib mesylate.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Talarico LR / 2010 / Idiopathic granulomatous and necrotising inflammatory disorders of the canine central nervous system : a review and future perspectives / J Small Anim Pract 51:138~149
O'Neill EJ / 2005 / Granulomatous meningoencephalomyelitis in dogs : a review / Ir Vet J 58:86
Mercier M / 2015 / Efficacy of glucocorticoid monotherapy for treatment of canine meningoencephalomyelitis of unknown etiology : a prospective study in 16 dogs / Vet Med Sci 1:16~22
Haouala A / 2011 / Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib / Blood 117:e75~e87
Kipar A / 1998 / Immunohistochemical characterization of inflammatory cells in brains of dogs with granulomatous meningoencephalitis / Vet Pathol 35:43~52
O'Neill EJ / 2005 / Granulomatous meningoencephalomyelitis in dogs : a review / Ir Vet J 58:86
Mercier M / 2015 / Efficacy of glucocorticoid monotherapy for treatment of canine meningoencephalomyelitis of unknown etiology : a prospective study in 16 dogs / Vet Med Sci 1:16~22
Haouala A / 2011 / Drug interactions with the tyrosine kinase inhibitors imatinib, dasatinib, and nilotinib / Blood 117:e75~e87
Kipar A / 1998 / Immunohistochemical characterization of inflammatory cells in brains of dogs with granulomatous meningoencephalitis / Vet Pathol 35:43~52
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Exacerbation of Psoriasis after Imatinib Mesylate Treatment
Annals of Dermatology
2016 .01
-
Imatinib Mesylate-Induced Erythema Multiforme: Recurrence after Rechallenge with 200 mg/day Imatinib
Annals of Dermatology
2015 .01
-
전이성 위장관 기질종양의 수술 후 완치
Korean Journal of Helicobacter Upper Gastrointestinal Research
2018 .01
-
Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor
영남의대학술지
2019 .01
-
Imatinib-induced hepatitis treated by corticosteroids in a patient with metastatic gastrointestinal stromal tumor
Journal of Yeungnam Medical Science
2019 .01
-
Long-term follow-up of optic neuritis associated with meningoencephalitis of unknown etiology in a Maltese dog
Korean Journal of Veterinary Research(대한수의학회지)
2019 .07
-
A rare case of osteonecrosis of the jaw related to imatinib
대한구강악안면외과학회지
2017 .01
-
Hyperpigmentation of the hard palate mucosa in a patient with chronic myeloid leukaemia taking imatinib
Maxillofacial Plastic Reconstructive Surgery
2017 .12
-
Use of generic imatinib as first-line treatment in patients with chronic myeloid leukemia (CML): the GIMS (Glivec to Imatinib Switch) study
Blood Research
2020 .01
-
Imatinib Mesylate-Induced Acquired Dermal Melanocytosis and Acquired Bilateral Nevus of Ota-Like Macules
Annals of Dermatology
2021 .01
-
Severe Imatinib-Associated Skin Rash in Gastrointestinal Stromal Tumor Patients: Management and Clinical Implications
Cancer Research and Treatment
2016 .01
-
Adjuvant Imatinib Treatment for 5 Years versus 3 Years in Patients with Ruptured Localized Gastrointestinal Stromal Tumor: A Retrospective Analysis
Cancer Research and Treatment
2022 .10
-
Clinical outcomes of traumatic brain injury dogs underwent CT or MRI
한국가축위생학회지
2024 .06
-
Prednisolone-induced diabetes mellitus without pancreatic islet pathology in a dog
Journal of Biomedical and Translational Research
2021 .01
-
Imatinib Mesylate Versus Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Chronic Myelogenous Leukemia
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Effect of imatinib mesylate and rapamycin on the preformed intimal hyperplasia in rat carotid injury model
Annals of Surgical Treatment and Research
2015 .02
-
Clinical Observations on Treatment for Chinese Patients with Gastrointestinal Stromal Tumors
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
부신으로 전이된 위장관기질종양 1예
대한내과학회지
2017 .01
-
Whole-Genome and Transcriptome Sequencing Identified NOTCH2 and HES1 as Potential Markers of Response to Imatinib in Desmoid Tumor (Aggressive Fibromatosis): A Phase II Trial Study
Cancer Research and Treatment
2022 .10
-
An outpatient case study of Cyaplex F: mitigated adverse effects associated with Imatinib
셀메드
2023 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0