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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 영남대학교 의과대학 Journal of Yeungnam Medical Science Yeungnam University Journal of Medicine 제36권 제2호
- 발행연도
- 2019.1
- 수록면
- 155 - 158 (4page)
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초록· 키워드
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Imatinib mesylate is currently used as the first-line treatment for metastatic gastrointestinal stromal tumors (GISTs). Imatinib-induced hepatotoxicity in patients with GIST is very rare. Its features vary from subclinical elevation of serum aminotransferase to clinically apparent acute hepatitis, which is associated with immunologic reactions. Imatinib-induced hepatotoxicity with autoimmune-like features can be treated by the discontinuation of imatinib mesylate and the administration of oral steroids. Here, we report a case of late-onset imatinib-induced hepatitis with autoimmune-like features in a patient with metastatic GIST, which was improved by oral corticosteroids.
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참고문헌 (14)
참고문헌 신청
Pariente A / 2006 / Imatinib mesylate-induced acute hepatitis in a patient treated for gastrointestinal stromal tumour / Eur J Gastroenterol Hepatol 18:785~787
Tonyali O / 2010 / Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors / Med Oncol 27:768~773
Seidel C / 2012 / Imatinib-induced liver cirrhosis in a patient with advanced gastrointestinal stroma tumor (GIST) / BMC Cancer 12:186
Yachoui R / 2014 / Early onset imatinib mesylate-induced hepatotoxicity in a patient with gastrointestinal stromal tumors / Am J Ther 21:e148~e150
Ferrero D / 2006 / Corticosteroids can reverse severe imatinibinduced hepatotoxicity / Haematologica 91(6 Suppl):ECR27
Tonyali O / 2010 / Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors / Med Oncol 27:768~773
Seidel C / 2012 / Imatinib-induced liver cirrhosis in a patient with advanced gastrointestinal stroma tumor (GIST) / BMC Cancer 12:186
Yachoui R / 2014 / Early onset imatinib mesylate-induced hepatotoxicity in a patient with gastrointestinal stromal tumors / Am J Ther 21:e148~e150
Ferrero D / 2006 / Corticosteroids can reverse severe imatinibinduced hepatotoxicity / Haematologica 91(6 Suppl):ECR27
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