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자료유형
학술저널
저자정보
유병혁 (경북대학교병원) 박지연 (경북대학교) 박기범 (경북대학교) 권오경 (경북대학교) 이승수 (경북대학교) 정호영 (경북대학교)
저널정보
대한위암학회 Journal of Gastric Cancer Journal of Gastric Cancer 제20권 제3호
발행연도
2020.1
수록면
328 - 336 (9page)

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Purpose: The standard treatment for stage IB gastric cancer is curative surgery alone, but some patients show poor survival with disease recurrence after curative surgery. The aim of this study was to identify prognostic factors of recurrence and long-term survival in patients with stage IB gastric cancer after surgery. Materials and Methods: We retrospectively reviewed data from 253 patients with stage IB gastric cancer who underwent gastrectomy between 2011 and 2016 at Kyungpook National University Chilgok Hospital and analyzed the clinicopathological characteristics associated with recurrence and survival. Results: Fourteen patients experienced recurrence with a mean follow-up of 54.1 months. Two of these patients had locoregional recurrence and 12 patients had systemic recurrence. The median interval between the operation day and the day of recurrence was 11 months (range 4?56 months). Multivariate analysis revealed that lymphatic vessel invasion (LVI) (hazard ratio [HR], 3.851; 95% confidence interval [CI], 1.264?11.732) and the elderly (age≥65) (HR, 3.850; 95% CI, 1.157?12.809) were independent risk factors for recurrence after surgery. The LVI (HR, 3.630; 95% CI, 1.105?11.923) was the independent prognostic factors for disease-specific survival (DSS). The 5-year DSS rates were 96.8% in patients who did not have LVI, and 89.3% in patients who had LVI. Conclusions: This study shows that LVI was associated with recurrence and poor survival in patients with stage IB gastric cancer after curative gastrectomy. Patients diagnosed with LVI require careful attention for systemic recurrence during the follow-up period.

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