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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 364 - 364 (1page)
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Streptomyces rapamycinicus is one of the producers of the clinically important immunosupressant rapamycin, and thus has been regarded as a biologically valuable microorganism. This Streptomyces strain possesses an exceptional biosynthetic diversity as the bioinformatic analysis of its genome sequences revealed the presence of total 51 different biosynthetic gene clusters (BGCs) such as PKS and NRPS gene clusters.
Among the predicted BGCs in S. rapamycinicus, we have focused on the BGC 41 that is cryptic BGC harboring reducing type II PKS (polyketide synthase) genes predicted to be involved in the polyene biosynthesis which is rare family of natural products. Through phylogenetic analysis, we identifi ... 전체 초록 보기
Among the predicted BGCs in S. rapamycinicus, we have focused on the BGC 41 that is cryptic BGC harboring reducing type II PKS (polyketide synthase) genes predicted to be involved in the polyene biosynthesis which is rare family of natural products. Through phylogenetic analysis, we identifi ... 전체 초록 보기
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