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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
Tinoco Hector A. (Universidad Autónoma de Manizales) Cardona Carlos I. (Universidad Autónoma de Manizales) Marín-Berrio Maribel L. F. (Universidad Autónoma de Manizales) García-Grisales Juliana (Universidad Autónoma de Manizales) Gomez Juan P. (Universidad Autónoma de Manizales) Roldan Samuel I. (Centro de Innovación Roldan) Peña Fabio M. (Universidad Autónoma de Manizales) Brinek Adam (Central European Institute of Technology - Brno University of Technology) Kalasová Dominika (Central European Institute of Technology - Brno University of Technology) Kaiser Jozef (Central European Institute of Technology - Brno University of Technology) Zikmund Tomas (Central European Institute of Technology - Brno University of Technology)
저널정보
대한의용생체공학회 Biomedical Engineering Letters (BMEL) Biomedical Engineering Letters (BMEL) Vol.10 No.4
발행연도
2020.1
수록면
603 - 617 (15page)

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Bone presents different systemic functionalities as calcium phosphate reservoir, organ protection, among others. For that reason, the bone health conditions are essential to keep in equilibrium the metabolism of several body systems. Different technologies exist to diagnose bone conditions with invasive methods based on ionizing radiation. Therefore, there is a challenge to develop new ways to evaluate bone alterations in a noninvasive form. This study shows the assessment of a piezo-actuated device acting on a human tooth for the bio-monitoring of bone alterations. The bone diagnosis is performed by applying the electromechanical impedance technique (EMI), commonly used in structural health monitoring. For the experimental tests, five bone samples were prepared, and one was chosen as the monitoring. All samples were put in a decalcifying substance (TBD1 acid–base) at different times to emulate localized bone mineral alterations. Bone reductions were computed by using X-ray micro-computed tomography analyzing the morphometry. Electrical resistance measurements (piezo-device) were taken for the monitoring specimen meanwhile it was partially decalcified during 8520 seconds. In the frequency spectrum, several observation windows showed that the bone alterations gradually changed the electrical resistance signals which were quantified statistically. Results evidenced that the bone density changes are correlated with the electrical resistance measurements; these changes presented an exponential behavior as much as in the calculated index, and bone mineral reduction. The results demonstrated that bone alterations exhibit linear dependence with the computed statistical indexes. This result confirms that it is possible to observe the bone changes from the teeth as a future application.
#Bone mass reduction Bone mineral alterations Bio-monitoring Spectroscopy Electromechanical impedance technique Bone mineral density Micro-CT Piezo-device Structural health monitoring

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참고문헌 (50)

참고문헌 신청
Hernlund E / 2013 / Osteoporosis in the European Union : medical management, epidemiology and economic burden / Arch Osteoporos 8(1?2):13 google schola Melton LJ 3rd / 1995 / How many women have osteoporosis now / J Bone Miner Res 10:175~177 google schola Kanis JA / 2000 / Long-term risk of osteoporotic fracture in Malmö / Osteoporos Int 11(669?674):7 google schola Van Staa TP / 2001 / Epidemiology of Fractures in England and Wales / Bone 29:517~522 google schola Kinds MB / 2011 / Feasibility of bone density evaluation using plain digital radiography / Osteoarthritis Cartil 19(11):1343~1348 google schola

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