지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 279 - 283 (5page)
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초록· 키워드
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Background: Patients with chronic liver disease (CLD) planned for liver transplantation (LT) often show severe thrombocytopenia, but there is a lack of evidence in deciding the threshold for prophylactic platelet transfusion.Case: A 47-year-old women with acute liver failure was referred for LT. Despite daily transfusion of platelets, platelet counts remained under 10,000/µl. During LT, 2 units of single donor platelets (SDP) were transfused. Although platelet counts remained extremely low (3,000–4,000/µl) no diffuse oozing was observed and the blood loss was 860 ml. Postoperatively, there was no sign of active bleeding or oozing, and the patient received only 1 unit SDP transfusion.Conclusions: CLD patients may have severe thrombocytopenia. However, primary hemostasis may not be significantly hindered due to the existence of rebalanced hemostasis. Prophylactic platelet transfusion in these patients should not be decided based on platelet counts only, but also take other coagulation tests and clinical signs into consideration.
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참고문헌 (15)
참고문헌 신청
Giannini EG / 2006 / Review article : thrombocytopenia in chronic liver disease and pharmacologic treatment options / Aliment Pharmacol Ther 23:1055~1065
Estcourt LJ / 2017 / Guidelines for the use of platelet transfusions / Br J Haematol 176:365~394
Saab S / 2019 / Management of thrombocytopenia in patients with chronic liver disease / Dig Dis Sci 64:2757~2768
Bang SR / 2010 / Predictors of high intraoperative blood loss derived by simple and objective method in adult living donor liver transplantation / Transplant Proc 42:4148~4150
한보배 / 2018 / Anesthetic management of a chronic liver disease patient with very low platelet counts by considering a rebalanced hemostasis - A case report - / Anesthesia and Pain Medicine 13(4):419~422
Estcourt LJ / 2017 / Guidelines for the use of platelet transfusions / Br J Haematol 176:365~394
Saab S / 2019 / Management of thrombocytopenia in patients with chronic liver disease / Dig Dis Sci 64:2757~2768
Bang SR / 2010 / Predictors of high intraoperative blood loss derived by simple and objective method in adult living donor liver transplantation / Transplant Proc 42:4148~4150
한보배 / 2018 / Anesthetic management of a chronic liver disease patient with very low platelet counts by considering a rebalanced hemostasis - A case report - / Anesthesia and Pain Medicine 13(4):419~422
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