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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 156 - 161 (6page)
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Purpose: To prospectively evaluate the diagnostic yield of multiparametric magnetic resonance imaging (mpMRI)-fusion, transrectal ultrasound (TRUS)-guided prostate biopsies for detection of prostate cancer in an Asian population with a low incidence of prostate cancer. Materials and Methods: A total of 131 males with suspected prostate cancer were recruited to undergo fusion biopsy with the Artemis prostate fusion biopsy device (Eigen, Grass Valley, CA, USA). All patients underwent standard 12-core systematic biopsies in addition to biopsies targeted at the mpMRI-identified abnormal regions. Yield from the standard cores was compared with that from the targeted cores. Gleason scores of 4+3 or higher were considered significant. Results: The mean age of the patients was 63.54±7.96 years and the mean prostate-specific antigen value was 9.75±5.35 ng/mL. A total of 36 patients had cancer, of which 3 (8.3%) were detected only on standard cores and 3 (8.3%) only on targeted cores. Of the clinically significant cancers (n=30), targeted biopsy detected a higher number (28/30, 93.3%) than standard biopsy (21/30, 70.0%). A total of 6 of 8 cancers (75.0%) that were insignificant on standard biopsy were upgraded to significant cancer on targeted cores. Conclusions: Eight percent of cancers were detected only on MRI-TRUS fusion-targeted biopsies, whereas the method upgraded more than two-thirds of insignificant cancers to significant cancers. Fusion biopsies thus provide incremental information over standard TRUS biopsies in the diagnosis of significant prostate cancer in populations with a low incidence of prostate cancer.
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참고문헌 (25)
참고문헌 신청
Babaian RJ / 2000 / A comparative analysis of sextant and an extended 11-core multisite directed biopsy strategy / J Urol 163:152~157
Ouzzane A / 2011 / Combined multiparametric MRI and targeted biopsies improve anterior prostate cancer detection, staging, and grading / Urology 78:1356~1362
Turkbey B / 2010 / Prostate cancer : value of multiparametric MR imaging at 3 T for detection--histopathologic correlation / Radiology 255:89~99
Puech P / 2009 / Dynamic contrast-enhanced-magnetic resonance imaging evaluation of intraprostatic prostate cancer : correlation with radical prostatectomy specimens / Urology 74:1094~1099
Seo JW / 2017 / PI-RADS version 2 : detection of clinically significant cancer in patients with biopsy gleason score 6 prostate cancer / AJR Am J Roentgenol 209:W1~9
Ouzzane A / 2011 / Combined multiparametric MRI and targeted biopsies improve anterior prostate cancer detection, staging, and grading / Urology 78:1356~1362
Turkbey B / 2010 / Prostate cancer : value of multiparametric MR imaging at 3 T for detection--histopathologic correlation / Radiology 255:89~99
Puech P / 2009 / Dynamic contrast-enhanced-magnetic resonance imaging evaluation of intraprostatic prostate cancer : correlation with radical prostatectomy specimens / Urology 74:1094~1099
Seo JW / 2017 / PI-RADS version 2 : detection of clinically significant cancer in patients with biopsy gleason score 6 prostate cancer / AJR Am J Roentgenol 209:W1~9
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