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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 555 - 571 (17page)
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초록· 키워드
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Sodium intake reduction has been emphasized because sodium adversely impacts health, especially blood pressure (BP), and the cardiovascular (CV) disease risk. However, data obtained from several cohort studies have raised questions regarding the effects of high sodium intake on BP and the CV disease risk. In the present study, we systematically reviewed the literature to evaluate these associations. Studies showing negative associations between urine sodium and BP and CV outcomes relied on estimated 24-hour urine sodium from spot urine that is inappropriate for determining sodium intake at an individual level. Furthermore, controversy about the association between 24-hour urine sodium and BP may have been caused by different characteristics of study populations, such as age distribution, ethnicity, potassium intake and the inclusion of patients with hypertension, the different statistical methods and BP measurement methods. Regarding the association between sodium intake and the CV disease risk, studies showing negative or J- or U-shaped associations used a single baseline measurement of 24-hour urine sodium in their analyses. However, recent studies that employed average of subsequently measured 24-hour urine sodium showed positive, linear associations between sodium intake and CV outcomes, indicating that controversies are caused by the different sodium intake measurement methods and analytic designs. In conclusion, the study shows that positive associations exist between sodium intake and BP, CV outcomes, and mortality, and that the argument that reducing sodium intake is dangerous is invalid. Sodium intake reduction should be recommended to all, and not limited to patients with hypertension or CV disease.
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참고문헌 (76)
참고문헌 신청
He FJ / 2009 / A comprehensive review on salt and health and current experience of worldwide salt reduction programmes / J Hum Hypertens 23:363~384
Adrogué HJ / 2007 / Sodium and potassium in the pathogenesis of hypertension / N Engl J Med 356:1966~1978
Nagata C / 2004 / Sodium intake and risk of death from stroke in Japanese men and women / Stroke 35:1543~1547
Kupari M / 1994 / Correlates of left ventricular mass in a population sample aged 36 to 37 years. Focus on lifestyle and salt intake / Circulation 89:1041~1050
Cianciaruso B / 1998 / Salt intake and renal outcome in patients with progressive renal disease / Miner Electrolyte Metab 24:296~301
Adrogué HJ / 2007 / Sodium and potassium in the pathogenesis of hypertension / N Engl J Med 356:1966~1978
Nagata C / 2004 / Sodium intake and risk of death from stroke in Japanese men and women / Stroke 35:1543~1547
Kupari M / 1994 / Correlates of left ventricular mass in a population sample aged 36 to 37 years. Focus on lifestyle and salt intake / Circulation 89:1041~1050
Cianciaruso B / 1998 / Salt intake and renal outcome in patients with progressive renal disease / Miner Electrolyte Metab 24:296~301
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