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초록· 키워드
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Flavonoids are a group of plant polyphenol secondary metabolites, which widely exist in plant systems. Recently, flavonoids from plant-based sources have been gaining more interest due to their versatile biological activities. The biological activities of flavonoids are dependent upon their chemical structures, which in turn rely on their structural class, level of hydroxylation, substitution pattern, connection position, existence of C2=C3 double bond, and level of polymerization. Flavonoids are considered nutraceuticals in diet. They help prevent many chronic and degenerative illnesses through various biological activities, such as free radical scavenging, anti-lipid peroxidation, and xanthine oxidase inhibition, as well as their anti-inflammatory, antimicrobial, and anti-cancer activities. The goal of the present review is to evaluate flavonoids’ chemical structural features and their biological activities as they relate to preventing chronic diseases affecting human health, and further navigate the relationship between the chemical structure and their biological function.
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등록된 정보가 없습니다.
참고문헌 (106)
참고문헌 신청
Ahmadi A / 2016 / Oxidative stress and cancer; the role of hesperidin, a citrus natural bioflavonoid, as a cancer chemoprotective agent / Nutr. Cancer 68:29~39
Alnajjar B / 2008 / Computational studies of natural flavonoids towards the discovery of a potential xanthine oxidase inhibitor
Amrutha K / 2014 / Discovery of lesser known flavones as inhibition of NF-kappaB signaling in MDA-MB-231 breast cancer cells-a SAR study / Bioorg. Med. Chem. Lett 24:4735~4742
Anna BB / 2005 / Acyated anthocyanins as stable, natural food colorants-a review / Pol. J. Food Nutr. Sci 14:107~116
Aoki T / 2000 / Flavonoids of leguminous plants : structure, biological activity, and biosynthesis / J. Plant Res 113:475~488
Alnajjar B / 2008 / Computational studies of natural flavonoids towards the discovery of a potential xanthine oxidase inhibitor
Amrutha K / 2014 / Discovery of lesser known flavones as inhibition of NF-kappaB signaling in MDA-MB-231 breast cancer cells-a SAR study / Bioorg. Med. Chem. Lett 24:4735~4742
Anna BB / 2005 / Acyated anthocyanins as stable, natural food colorants-a review / Pol. J. Food Nutr. Sci 14:107~116
Aoki T / 2000 / Flavonoids of leguminous plants : structure, biological activity, and biosynthesis / J. Plant Res 113:475~488
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