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논문 기본 정보

자료유형
학술저널
저자정보
Eunju Kim (Department of Gastroenterology Cha Bundang Medical Center Cha University College of Medicine Seongn) In Kyung Yoo (Department of Gastroenterology Cha Bundang Medical Center Cha University College of Medicine Seongn) Dong Keon Yon (Department of Pediatrics Cha Bundang Medical Center Cha University College of Medicine Seongnam Gye) Joo Young Cho (Department of Gastroenterology Cha Bundang Medical Center Cha University College of Medicine Seongn) Sung Pyo Hong (Department of Gastroenterology Cha Bundang Medical Center Cha University College of Medicine Seongn)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.26 No.2
발행연도
2020.1
수록면
274 - 280 (7page)

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Background/AimsIntegrated relaxation pressure (IRP) is a critical diagnostic criterion to define achalasia. However, there are some cases with typical symptoms and signs of achalasia but with normal IRP. The aim of this study is to evaluate the clinical characteristics of patients with achalasia with normal IRP and outcomes after peroral endoscopic myotomy (POEM). MethodsPatients with achalasia were collected in whom POEM was performed from November 2014 to April 2018 at CHA Bundang Medical Center. Achalasia with normal IRP was defined by findings compatible to achalasia in Eckardt score, endoscopy with endoscopic ultrasound, high-resolution manometry, impedance planimetry (EndoFlip), and timed esophagogram. ResultsPOEM was performed in 89 patients with achalasia; among them, 24 (27%) patients were diagnosed with achalasia with normal IRP. Patients with achalasia with normal IRP were older, had longer duration of symptom, and had a more tortuous esophagus. In EndoFlip, the distensibility index and cross-sectional area were higher in patients with normal IRP. Therapeutic outcomes showed no statistically significant differences. On correlation analysis, IRP had negative correlations with age, disease duration, and distensibility index. ConclusionsPatients with achalasia of normal IRP value were older and had longer disease duration and higher distensibility index and crosssectional area than patients with achalasia with abnormal relaxation of lower esophageal sphincter. Therapeutic outcomes were not different between the 2 groups.

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