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논문 기본 정보

자료유형
학술저널
저자정보
Seung Han Kim (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) 김홍배 (Department of Biosystems and Biomaterials Science and Engineering Seoul National University Seoul K) Hoon Jai Chun (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Hyuk Soon Choi (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Eun Sun Kim (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Bora Keum (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Yeon Seok Seo (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Yoon Tae Jeen (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Hong Sik Lee (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Soon Ho Um (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe) Chang Duck Kim (Division of Gastroenterology and Hepatology Department of Internal Medicine Institute of Gastrointe)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.26 No.3
발행연도
2020.1
수록면
410 - 416 (7page)

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Background/AimsGastric electrical stimulation (GES) is a feasible modality for the treatment of gastroparesis; however, the presently available device requires invasive surgical implantation for long-term stimulation and repeated surgical procedure after a period of time. This study is aimed at developing a wireless miniature GES device and testing its endoscopic insertion in animal models. MethodsEndoscopic gastric implantation of the GES device was performed on 5 healthy weaner pigs under general anesthesia. We created an endoscopic submucosal pocket and inserted the gastro-electrical stimulator. In vivo gastric slow waves were recorded and measured during electrical stimulation. A multi-channel recorder, called an electrogastrogram, was used to record the gastric myoelectrical activity in the study. ResultsThe gastric slow waves on the electrogastrogram were more consistent with GES on the gastric tissues compared to no stimulation. The frequency-to-amplitude ratio was also significantly altered after the electrical stimulation. ConclusionsGES is feasible with our minimally invasive wireless device. This technique has the potential to increase utilization of GES as a treatment alternative.

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