지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 345 - 355 (11page)
이용수
초록· 키워드
오류제보하기
Background: Viral vector-based therapeutic gene therapy is a potent strategy to enhance the intrinsic reparative abilities of human orthopaedic tissues. However, clinical application of viral gene transfer remains hindered by detrimental responses in the host against such vectors (immunogenic responses, vector dissemination to nontarget locations). Combining viral gene therapy techniques with tissue engineering procedures may offer strong tools to improve the current systems for applications in vivo. Methods: The goal of this work is to provide an overview of the most recent systems exploiting biomaterial technologies and therapeutic viral gene transfer in human orthopaedic regenerative medicine. Results: Integration of tissue engineering platforms with viral gene vectors is an active area of research in orthopaedics as a means to overcome the obstacles precluding effective viral gene therapy. Conclusions: In light of promising preclinical data that may rapidly expand in a close future, biomaterial-guided viral gene therapy has a strong potential for translation in the field of human orthopaedic regenerative medicine.
목차
등록된 정보가 없습니다.
참고문헌 (174)
참고문헌 신청
Goldring MB / 2007 / Osteoarthritis / J Cell Physiol 213:626~634
Madry H / 2011 / Cartilage repair and joint preservation : medical and surgical treatment options / Dtsch Arztebl Int 108:669~677
Tuan RS / 2013 / Cartilage regeneration / J Am Acad Orthop Surg 21:303~311
Brittberg M / 1994 / Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation / N Engl J Med 331:889~895
Knutsen G / 2004 / Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial / J Bone Joint Surg Am 86(A):455~464
Madry H / 2011 / Cartilage repair and joint preservation : medical and surgical treatment options / Dtsch Arztebl Int 108:669~677
Tuan RS / 2013 / Cartilage regeneration / J Am Acad Orthop Surg 21:303~311
Brittberg M / 1994 / Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation / N Engl J Med 331:889~895
Knutsen G / 2004 / Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial / J Bone Joint Surg Am 86(A):455~464
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Advances in adeno-associated virus based gene delivery systems for biomedical applications
한국생물공학회 학술대회
2019 .10
-
Gene Therapy for Bone Tissue Engineering
조직공학과 재생의학
2016 .01
-
Biomaterial-based gene therapy technologies for biomedical applications
한국생물공학회 학술대회
2015 .04
-
Directed Evolution of New Adeno-Associated Viral Vectors for Gene Therapy
한국생물공학회 학술대회
2015 .10
-
Development of High Efficiency Non-Viral Gene Delivery System
한국생물공학회 학술대회
2020 .06
-
Viral remodeling of the 4D nucleome
Experimental and Molecular Medicine
2024 .04
-
Development of a Non-viral Oral Gene Delivery System for the Treatment of Type 2 Diabetes Mellitus
한국생물공학회 학술대회
2023 .04
-
A Novel Approach of Viral Marketing in Social Networks
한국정보과학회 학술발표논문집
2017 .06
-
Development of Complex Biomaterials Systems and Their Applications in Regenerative Medicine
한국생물공학회 학술대회
2020 .06
-
Features of Various Nano Carrier for Ocular Disease Review
한국생물공학회 학술대회
2022 .09
-
Features of Various Nano Carrier for Ocular Disease Review
한국생물공학회 학술대회
2023 .04
-
Adeno-Associated Virus (AAV) Transferring Pro-Apoptotic Genes for Cancer Gene Therapy
한국생물공학회 학술대회
2015 .10
-
Development of Nano-self-assembly Gene Delivery System Using Cellulose Nanocrystal with Zinc/DNA Nanocluster
한국생물공학회 학술대회
2021 .04
-
The Development of Poly(amidoamine) Derivative Using NLS in Classical Protein Import
한국고분자학회 학술대회 연구논문 초록집
2021 .04
-
Oligopeptide complex for targeted non-viral gene delivery to adipocytes
한국고분자학회 학술대회 연구논문 초록집
2016 .10
-
Review of pDNA Gene Delivery System
한국생물공학회 학술대회
2021 .10
-
Oral GLP1 Gene Delivery by Bile Acid Based Non Viral Gene Delivery Carrier to Treat Type II Diabetes Mellitus
한국고분자학회 학술대회 연구논문 초록집
2020 .10
-
Wet-spinning of chitosan and heparin complex for viral gene delivery
한국고분자학회 학술대회 연구논문 초록집
2018 .04
-
In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative Medicine
조직공학과 재생의학
2018 .01
-
Three-Dimensional Printing in Tissue Engineering and Regenerative Medicine
조직공학과 재생의학
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0