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학술저널
저자정보
최아름 (이화여자대학교) 심기남 (이화여자대학교) Tae Oh Kim (Department of Internal Medicine Ewha Medical Research Institute Ewha Womans University College of M) Sang Yoon Kim (Department of Internal Medicine Ewha Medical Research Institute Ewha Womans University College of M) Jiyoung Lim (Department of Internal Medicine Ewha Medical Research Institute Ewha Womans University College of M) 태정현 (이화여자대학교) 문창모 (Department of Internal Medicine Ewha Medical Research Institute Ewha Womans University College of M) 김성은 (Department of Internal Medicine Ewha Medical Research Institute Ewha Womans University College of M) 정혜경 (이화여자대학교) 정성애 (이화여자대학교)
저널정보
대한상부위장관 헬리코박터학회 Korean Journal of Helicobacter Upper Gastrointestinal Research Korean Journal of Helicobacter Upper Gastrointestinal Research Vol.19 No.3
발행연도
2019.1
수록면
184 - 192 (9page)

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Background/Aims: Although endoscopic submucosal dissection (ESD) is an accepted treatment method for gastric neoplasm worldwide, metachronous recurrence often occurs. Here, we evaluated the risk factors for metachronous recurrence after ESD of gastric dysplasia or adenocarcinoma and also examined the effects of Helicobacter pylori (H. pylori) eradication. Materials and Methods: Among 400 patients who underwent endoscopic resection from February 2005 to December 2014 at Ewha Womans University Hospital, the medical records of 180 patients were retrospectively reviewed. Results: The enrolled patients included 118 men and 62 women, and their median age was 61.7±10.3 years. During a median follow- up period of 34.5 months, metachronous recurrence occurred in 21 (11.7%) patients. Multivariate analyses revealed that H. pylori eradication did not have any preventive effects on metachronous recurrence. A family history of gastric cancer was the only risk factor for metachronous recurrence after ESD of the gastric neoplasm. Conclusions: Metachronous recurrence was found to be related to family history of gastric cancer. However, H. pylori eradication had no preventive effects on metachronous recurrence after ESD of a gastric neoplasm. Therefore, intensive surveillance is required for patients who undergo ESD of a gastric neoplasm and have a family history of gastric cancer.

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