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논문 기본 정보

자료유형
학술저널
저자정보
Sung Kwon Kim (Department of Neurosurgery Gyeongsang National University Changwon) Jangsup Moon (Department of Neurology Rare Disease Center Seoul National University Hospital Seoul National Uni) Jin Mo Cho (Catholic Kwangdong University) Kyung Hwan Kim (Department of Neurosurgery Chungnam National University Hospital Chungnam National University Scho) 김세훈 (연세대학교 의과대학 세브란스병원) 김영일 (가톨릭대학교) Young Zoon Kim (Samsung Changwon Hospital Sungkyunkwan University School of Medicine) Ho Sung Kim (Asan Medical Center University of Ulsan College of Medicine Seoul Korea) 도윤식 (충북대학교) Jae-Sung Park (Department of Neurosurgery Seoul St. Mary’s Hospital College of Medicine The Catholic University) Ji Eun Park (Department of Radiology and Research Institute of Radiology University of Ulsan College of) 서영범 (영남대학교) Kyoung-Su Sung (Department of Neurosurgery Dong-A University) 송진호 (가톨릭대학교) Chan Woo Wee (Department of Radiation Oncology SMG-SNU Boramae Medical Center Seoul National University College) Wan-Soo Yoon (Department of Neurosurgery Incheon St. Mary's Hospital The Catholic University of Korea) 윤홍인 (연세대학교) Se-Hoon Lee (Division of Hematology/Oncology Department of Medicine Samsung Medical Center Sungkyunkwan Univer) Do Hoon Lim (Department of Radiation Oncology Samsung Medical Center) 임정호 (Department of Radiation Oncology CHA Bundang Medical Center CHA University School of Medicine) 장종희 (연세대학교) 한명훈 (한양대학교) 홍제범 (Department of Neurosurgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seou) Kihwan Hwang (Department of Neurosurgery Seoul National University Bundang Hospital Seoul National University Col) Chul-Kee Park (Seoul National University Hospital) 이연수 (가톨릭대학교) 곽호신 (국립암센터) KSNO Guideline Working Group (KSNO Guideline Working Group)
저널정보
대한뇌종양학회 Brain Tumor Research and Treatment Brain Tumor Research and Treatment Vol.8 No.1
발행연도
2020.1
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1 - 10 (10page)

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Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate national patterns of clinical practice about antiepileptic drug (AED) and steroid usage for management of brain tumors. Methods: A web-based survey was sent to all members of the KSNO by email. The survey included 9 questions of AED usage and 5 questions of steroid usage for brain tumor patients. All questions were developed by consensus of the Guideline Working Group. Results: The overall response rate was 12.8% (54/423). Regarding AED usage, the majority of respondents (95.2%) routinely prescribed prophylactic AEDs for patients with seizure at the peri/postoperative period. However, as many as 72.8% of respondents prescribed AED routinely for seizure-naive patients, and others prescribed AED as the case may be. The duration of AED prophylaxis showed wide variance according to the epilepsy status and the location of tumor. Levetiracetam (82.9%) was the most preferred AED for epilepsy prophylaxis. Regarding steroid usage, 90.5% of respondents use steroids in perioperative period, including 34.2% of them as a routine manner. Presence of peritumoral edema (90.9%) was considered as the most important factor determining steroid usage followed by degree of clinical symptoms (60.6%). More than half of respondents (51.2%) replied to discontinue the steroids within a week after surgery if there are no specific medical conditions, while 7.3% preferred slow tapering up to a month after surgery. Conclusion: The survey demonstrated the prevailing practice patterns on AED and steroid usage in neuro-oncologic field among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of brain tumor patients.
#Korean Society for Neuro-Oncology #Practice patterns #Brain tumors #Antiepileptic drugs #Steroids #Guideline Working Group

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참고문헌 (24)

참고문헌 신청
Sayegh ET / 2014 / Anticonvulsant prophylaxis for brain tumor surgery : determining the current best available evidence / J Neurosurg 121:1139~1147 google schola Klimek M / 2010 / Antiepileptic drug therapy in the perioperative course of neurosurgical patients / Curr Opin Anaesthesiol 23:564~567 google schola Sughrue ME / 2011 / Postoperative seizures following the resection of convexity meningiomas : are prophylactic anticonvulsants indicated? Clinical article / J Neurosurg 114:705~709 google schola Gutin PH / 1975 / Corticosteroid therapy in patients with cerebral tumors: benefits, mechanisms, problems, practicalities / Semin Oncol 2:49~56 google schola Weissman DE / 1987 / Corticosteroid toxicity in neuro-oncology patients / J Neurooncol 5:125~128 google schola

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