지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Introduction: Vitamin D has been shown to correlate with a variety of skin diseases including psoriasis, skin cancers and atopic dermatitis, because it is involved in innate and adaptive immunity. However, since most of the studies are conducted in the West countries, it is difficult to apply the results to Korean. Objective: To investigate the association between various dermatologic diseases and serum vitamin D levels in Korean. Methods: We retrospectively reviewed the serum levels of vitamin D in 206 patients who visited our clinic from November 2013 to February 2019 and diagnosed as psoriasis, vitiligo, skin cancers, atopic dermatitis and alopecia areata. The severity of psoriasis was assessed by Psoriasis Area Severity Index (PASI), and the vitamin D levels of 38 healthy controls without other disease were compared with those of psoriasis. Results: The average serum vitamin D level in patients was found to be 17.09 10.93 ng/mL and 152 (72.8%) patients had serum vitamin D levels below 20 ng/mL. Serum vitamin D levels were lowest in patients with atopic dermatitis (15.97 ng/mL). In psoriasis patients, there was no difference in serum vitamin D levels between healthy controls (p>0.05), and there was no association between PASI and serum vitamin D levels (p>0.05). Conclusion: It is necessary to pay attention to apply the results of the association between serum vitamin D levels and these dermatologic disease reported in foreign countries.
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참고문헌 (17)
참고문헌 신청
Umar M / 2018 / Vitamin D and the Pathophysiology of Inflammatory Skin Diseases / Skin Pharmacol Physiol 31:74~86
김원정 / 2015 / 한국인 아토피피부염, 건선, 만성특발두드러기 환자에서 임상적 중증도와 혈중 비타민 D 농도와의 연관성 / 대한피부과학회지 53(3):209~216
Zittermann A / 2010 / Nonclassical vitamin D action / Nutrients 2:408~425
Amon U / 2018 / Serum 25-hydroxyvitamin D levels in patients with skin diseases including psoriasis, infections, and atopic dermatitis / Dermatoendocrinol 10:e1442159
Park JH / 2018 / Vitamin D status in South Korean population: Seven-year trend from the KNHANES / Medicine (Baltimore) 97:e11032
김원정 / 2015 / 한국인 아토피피부염, 건선, 만성특발두드러기 환자에서 임상적 중증도와 혈중 비타민 D 농도와의 연관성 / 대한피부과학회지 53(3):209~216
Zittermann A / 2010 / Nonclassical vitamin D action / Nutrients 2:408~425
Amon U / 2018 / Serum 25-hydroxyvitamin D levels in patients with skin diseases including psoriasis, infections, and atopic dermatitis / Dermatoendocrinol 10:e1442159
Park JH / 2018 / Vitamin D status in South Korean population: Seven-year trend from the KNHANES / Medicine (Baltimore) 97:e11032
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