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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 140 - 155 (16page)
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초록· 키워드
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Sex steroids influence the maintenance and growth of muscles. Decline in androgens, estrogens and progesterone by aging leads to the loss of muscular function and mass, sarcopenia. These steroid hormones can interact with different signaling pathways through their receptors. To date, sex steroid hormone receptors and their exact roles are not completely defined in skeletal and smooth muscles. Although numerous studies focused on the effects of sex steroid hormones on different types of cells, still many unexplained molecular mechanisms in both skeletal and smooth muscle cells remain to be investigated. In this paper, many different molecular mechanisms that are activated or inhibited by sex steroids and those that influence the growth, proliferation, and differentiation of skeletal and smooth muscle cells are reviewed. Also, the similarities of cellular and molecular pathways of androgens, estrogens and progesterone in both skeletal and smooth muscle cells are highlighted. The reviewed signaling pathways and participating molecules can be targeted in the future development of novel therapeutics.
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등록된 정보가 없습니다.
참고문헌 (267)
참고문헌 신청
Muller MJ / 2014 / Assessment and definition of lean body mass deficiency in the elderly / Eur J Clin Nutr 68:1220~1227
Baumgartner RN / 1998 / Epidemiology of sarcopenia among the elderly in New Mexico / Am J Epidemiol 147:755~763
Morley JE / 2012 / Sarcopenia in the elderly / Fam Pract 29(Suppl. 1):i44~i48
Morley J / 2008 / Sarcopenia: diagnosis and treatment / J Nutr Health Aging 12:452~456
Korea National Statistical Office / Korea National Statistical Office. Statistics on the aged
Baumgartner RN / 1998 / Epidemiology of sarcopenia among the elderly in New Mexico / Am J Epidemiol 147:755~763
Morley JE / 2012 / Sarcopenia in the elderly / Fam Pract 29(Suppl. 1):i44~i48
Morley J / 2008 / Sarcopenia: diagnosis and treatment / J Nutr Health Aging 12:452~456
Korea National Statistical Office / Korea National Statistical Office. Statistics on the aged
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