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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 155 - 158 (4page)
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초록· 키워드
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Objectives: Vitamin D deficiency has been shown to influence the development of some cardiovascular disease. In this study, the association between the existence of coronary artery plaque and vitamin D was examined among participants who were not previously diagnosed with coronary artery disease. Methods: A total of 339 participants (246 men and 93 women) who visited a health examination center for check-up including blood test for serum vitamin D level and coronary computed tomography angiography (CCTA) were selected for this study. Results: Among the total 339 participants, 106 displayed coronary artery plaques. The serum 25-hydroxy vitamin D (25(OH)D) level of the group with plaque was lower than that of the group without (17.7 ± 7.72 ng/mL vs. 19.6 ± 7.12 ng/mL, P ¼ 0.0316). The group with plaque had higher incidence rates of diabetes mellitus, hypertension, and dyslipidemia than that without (P ¼ 0.0078, P ¼ 0.0065, and P ¼ 0.0174, respectively). The former displayed higher serum glucose and glycated hemoglobin levels than the latter (P ¼ 0.0055 and P ¼ 0.0137, respectively). The group with plaque showed higher systolic and diastolic blood pressure than that without (P < 0.0001 and P ¼ 0.0012, respectively). Stepwise multivariate logistic regression analysis revealed that 25(OH)D (coefficient, 『0.06; odd ratio, 0.9433; 95% confidence interval, 0.8967e0.9924), age, and sex were independently related with presence of coronary artery plaque. Conclusions: Relatively low vitamin D level was observed among participants with plaque, which was determined through CCTA during a health examination. Plaque formation and serum 25(OH)D level showed inverse relationship.
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참고문헌 (19)
참고문헌 신청
Siasos G / 2013 / Vitamin D serum levels are associated with cardiovascular outcome in coronary artery disease / Eur Heart J 34(Suppl 1):2486
Melamed ML / 2008 / Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004 / Arterioscler Thromb Vasc Biol 28:1179~1185
Schierbeck LL / 2011 / Parathyroid hormone and vitamin Demarkers for cardiovascular and all cause mortality in heart failure / Eur J Heart Fail 13:626~632
Akin F / 2012 / Serum vitamin D levels are independently associated with severity of coronary artery disease / J Investig Med 60:869~873
Watson KE / 1997 / Active serum vitamin D levels are inversely correlated with coronary calcification / Circulation 96:1755~1760
Melamed ML / 2008 / Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004 / Arterioscler Thromb Vasc Biol 28:1179~1185
Schierbeck LL / 2011 / Parathyroid hormone and vitamin Demarkers for cardiovascular and all cause mortality in heart failure / Eur J Heart Fail 13:626~632
Akin F / 2012 / Serum vitamin D levels are independently associated with severity of coronary artery disease / J Investig Med 60:869~873
Watson KE / 1997 / Active serum vitamin D levels are inversely correlated with coronary calcification / Circulation 96:1755~1760
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