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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.70 No.2
- 발행연도
- 2017.1
- 수록면
- 177 - 183 (7page)
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초록· 키워드
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Background: Hospital-acquired pneumonia (HAP) is a common complication after abdominal surgery. The aim of this study was to evaluate the role of procalcitonin (PCT) and C-reactive protein (CRP) as early biomarkers for the diagnosis of postoperative HAP after abdominal surgery. Methods: This study was conducted on 100 patients undergoing abdominal surgery. White blood cell counts, highest body temperature, and serum levels of CRP and PCT were recorded preoperatively and daily postoperatively until postoperative day (POD) 5. Chest radiography was performed preoperatively and daily postoperatively until POD 5. Results: HAP was diagnosed in 14% of patients. Regarding the biomarkers studied after POD 1, CRP and PCT were significantly higher in patients with HAP than in those without HAP (P < 0.05). On POD 2, PCT had higher sensitivity and specificity (84% and 72%, respectively) than those for CPR (70% and 60%, respectively). The cut-off value of PCT on POD 2 was 1.4 ng/ml. On POD 3, 4, and 5, the sensitivity and specificity of PCT and CRP were not significantly different. Conclusions: PCT and CRP are accurate biomarkers for early prediction of postoperative HAP after abdominal surgery. The diagnostic ability of PCT was significantly better than that of CRP on POD 2. After POD 2, the diagnostic ability was not significantly different between the biomarkers.
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참고문헌 (29)
참고문헌 신청
Smetana GW / 2006 / Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians / Ann Intern Med 144:581~595
Pepys MB / 2003 / C-reactive protein: a critical update / J Clin Invest 111:1805~1812
MacKay GJ / 2011 / C-reactive protein as a predictor of postoperative infective complications following elective colorectal resection / Colorectal Dis 13:583~587
Dutta S / 2011 / Persistent elevation of C-reactive protein following esophagogastric cancer resection as a predictor of postoperative surgical site infectious complications / World J Surg 35:1017~1025
Garcia-Granero A / 2013 / Procalcitonin and C-reactive protein as early predictors of anastomotic leak in colorectal surgery: a prospective observational study / Dis Colon Rectum 56:475~483
Pepys MB / 2003 / C-reactive protein: a critical update / J Clin Invest 111:1805~1812
MacKay GJ / 2011 / C-reactive protein as a predictor of postoperative infective complications following elective colorectal resection / Colorectal Dis 13:583~587
Dutta S / 2011 / Persistent elevation of C-reactive protein following esophagogastric cancer resection as a predictor of postoperative surgical site infectious complications / World J Surg 35:1017~1025
Garcia-Granero A / 2013 / Procalcitonin and C-reactive protein as early predictors of anastomotic leak in colorectal surgery: a prospective observational study / Dis Colon Rectum 56:475~483
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