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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 213 - 219 (7page)
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Background: The differences between neuromuscular blocking (NMB) drugs on the efficacy of intraoperative motor-evoked potential (MEP) monitoring have not been established through clinical study. We compared the effects of vecuronium and cisatracurium on the efficacy of intraoperative MEP monitoring. Methods: We enrolled 72 patients who had undergone neurosurgery with MEP monitoring. We randomly allocated the subjects into one of two groups, in whom we maintained continuous intravenous vecuronium (Group V) or cisatracurium (Group C) infusion during the surgeries; the target partial NMB for maintenance was T1/Tc 50% (T1, first twitch of TOF response; Tc, control response of T1 before NMB drug injection). We compared the means and coefficients of variation (CV, %) of all measured MEP amplitudes and the frequencies of NMB drug dose changes. Results: The means and CVs of MEP amplitude and latency in all four limbs did not differ significantly between the groups, although we did change the continuous NMB drug doses in group V significantly less often than in group C. Conclusions: There were no significant differences between vecuronium and cisatracurium on the MEP variability and mean amplitudes. However, cisatracurium needed more frequent dose changes to maintain T1/Tc 50%.
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참고문헌 (19)
참고문헌 신청
Mendiratta A / 2009 / Neurophysiologic intraoperative monitoring of scoliosis surgery / J Clin Neurophysiol 26:62~69
Sloan TB / 2002 / Anesthesia for intraoperative neurophysiologic monitoring of the spinal cord / J Clin Neurophysiol 19:430~443
Minahan RE / 2000 / The effect of neuromuscular blockade on pedicle screw stimulation thresholds / Spine (Phila Pa 1976) 25:2526~2530
Blair EA / 1994 / Effect of neuromuscular blockade on facial nerve monitoring / Am J Otol 15:161~167
Cai YR / 2009 / Electromyographic monitoring of facial nerve under different levels of neuromuscular blockade during middle ear microsurgery / Chin Med J (Engl) 122:311~314
Sloan TB / 2002 / Anesthesia for intraoperative neurophysiologic monitoring of the spinal cord / J Clin Neurophysiol 19:430~443
Minahan RE / 2000 / The effect of neuromuscular blockade on pedicle screw stimulation thresholds / Spine (Phila Pa 1976) 25:2526~2530
Blair EA / 1994 / Effect of neuromuscular blockade on facial nerve monitoring / Am J Otol 15:161~167
Cai YR / 2009 / Electromyographic monitoring of facial nerve under different levels of neuromuscular blockade during middle ear microsurgery / Chin Med J (Engl) 122:311~314
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